CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017496
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Inactive phospholipase D5 
Protein Synonyms/Alias
 Inactive PLD 5; Inactive choline phosphatase 5; Inactive phosphatidylcholine-hydrolyzing phospholipase D5; PLDc 
Gene Name
 PLD5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
200SKVLEALKLKGAEVTubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
 DOMAIN 215 242 PLD phosphodiesterase 1.
 DOMAIN 434 460 PLD phosphodiesterase 2.
 CARBOHYD 121 121 N-linked (GlcNAc...) (Potential).
 CARBOHYD 302 302 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Glycoprotein; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 536 AA 
Protein Sequence
MEIRQHEWLS ASPHEGFEQM RLKSRPKEPS PSLTRVGANF YSSVKQQDYS ASVWLRRKDK 60
LEHSQQKCIV IFALVCCFAI LVALIFSAVD IMGEDEDGLS EKNCQNKCRI ALVENIPEGL 120
NYSENAPFHL SLFQGWMNLL NMAKKSVDIV SSHWDLNHTH PSACQGQRLF EKLLQLTSQN 180
IEIKLVSDVT ADSKVLEALK LKGAEVTYMN MTAYNKGRLQ SSFWIVDKQH VYIGSAGLDW 240
QSLGQMKELG VIFYNCSCLV LDLQRIFALY SSLKFKSRVP QTWSKRLYGV YDNEKKLQLQ 300
LNETKSQAFV SNSPKLFCPK NRSFDIDAIY SVIDDAKQYV YIAVMDYLPI SSTSTKRTYW 360
PDLDAKIREA LVLRSVRVRL LLSFWKETDP LTFNFISSLK AICTEIANCS LKVKFFDLER 420
ENACATKEQK NHTFPRLNRN KYMVTDGAAY IGNFDWVGND FTQNAGTGLV INQADVRNNR 480
SIIKQLKDVF ERDWYSPYAK TLQPTKQPNC SSLFKLKPLS NKTATDDTGG KDPRNV 536 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0003824; F:catalytic activity; IEA:InterPro. 
Interpro
 IPR001736; PLipase_D/transphosphatidylase. 
Pfam
  
SMART
 SM00155; PLDc 
PROSITE
 PS50035; PLD 
PRINTS