CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030959
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ53353, highly similar to ATP-binding cassette sub-family D member 3 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
85KERAVVDKVFFSRLIubiquitination[1]
284KMTITEQKYEGEYRYubiquitination[1, 2]
310IAFYNGNKREKQTVHubiquitination[2, 3]
371LSHPRHLKSTHSELLubiquitination[1]
528LTKPERGKLFYVPQRubiquitination[3]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 683 AA 
Protein Sequence
MAAFSKYLTA RNSSLAGAAF LLLCLLHKRR RALGLHGYFM ETWREKSDEV MGELTDHVTH 60
CKKSGKPPLQ NNEKEGKKER AVVDKVFFSR LIQILKIMVP RTFCKETGYL VLIAVMLVSR 120
TYCDVWMIQN GTLIESGIIG RSRKDFKRYL LNFIAAMPLI SLVNNFLKYG LNELKLCFRV 180
RLTKYLYEEY LQAFTYYKMG NLDNRIANPD QLLTQDVEKF CNSVVDLYSN LSKPFLDIVL 240
YIFKLTSAIG AQGPASMMAY LVVSGLFLTR LRRPIGKMTI TEQKYEGEYR YVNSRLITNS 300
EEIAFYNGNK REKQTVHSVF RKLVEHLHNF ILFRFSMGFI DSIIAKYLAT VVGYLVVSRP 360
FLDLSHPRHL KSTHSELLED YYQSGRMLLR MSQALGRIVL AGREMTRLAG FTARITELMQ 420
VLKDLNHGKY ERTMVSQQEK DIEGVQVIPL IPGAGEIIIA DNIIKFDHVP LATPNGDVLI 480
RDLNFEVRSG ANVLICGPNG CGKSSLFRVL GELWPLFGGR LTKPERGKLF YVPQRPYMTL 540
GTLRDQVIYP DGREDQKRKG ISDLVLKEYL DNVQLGHILE REGGWDSVQD WMDVLSGGEK 600
QRMAMARLFY HKPQFAILDE CTSAVSVDVE GYIYSHCRKV GITLFTVSHR KSLWKHHEYY 660
LHMDGRGNYE FKQITEDTVE FGS 683 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR010509; ABC_Ald_N.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR005283; FA_transporter.
 IPR027417; P-loop_NTPase. 
Pfam
 PF06472; ABC_membrane_2
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS