CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029898
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 SRC kinase-signaling inhibitor 1 
Protein Synonyms/Alias
  
Gene Name
 Srcin1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
124FMDHLKSKYPQHALAubiquitination[1]
463PGAGGLYKRGSVRSLubiquitination[1]
560FAESPGGKARSTGSAubiquitination[1]
708GQLQQLRKLQLQNQEubiquitination[1]
802EEKALVLKQLGETLTubiquitination[1]
963ALTQYSAKDINRLLEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1198 AA 
Protein Sequence
MQPWQCLRRF ALAWWERTAE GRARSPREEV GPRDPGGRGE PDPERSSPPM LSADDAEYPR 60
EYRTLGGGGG GGSGGRRFSN VGLVHTSERR HTVIAAQSLE ALSGLQKADA DRKRDAFMDH 120
LKSKYPQHAL ALRGQQDRMR EQQPNYWSFK TRSSRHTQGA QPGLADQAAK LSYASAESLE 180
TMSEAELPLG FSRMNRFRQS LPLSRSASQT KLRSPGVLFL QFGEETRRVH ITHEVSSLDT 240
LHALIAHMFP QKLTMGMLKS PNTAILIKDE ARNVFYELED VRDIQDRSII KIYRKEPLYA 300
AFPGSHLTNG DLRREMVYAS RESSPTRRLN NLSPASHLAS SSPPPGLPSG LPSGLPSGSP 360
SRSRLSYAGG RPPSYAGSPV HHAAERLGGA PTGQGVSPSP SAILERRDVK PDEDLAGKAG 420
GMVLVKGEGL YADPYGLLHE GRLSLAAAAG DPFAYPGAGG LYKRGSVRSL STYSAAALQS 480
DLEDSLYKAG AGGPLYGDGY GFRLPPSSPQ KLADVSAPSG GPPPPHSPYS GPPSRGSPVR 540
QSFRKDSGSS SVFAESPGGK ARSTGSASTA GAPPSELFPG PGERSLVGFG PPVPAKDTET 600
RERMEAMEKQ IASLTGLVQS ALLRGSEPET PSEKVEGSNG AATPSAPVCG SGSKSSGATP 660
VSGPPPPSAS STPAGQPTAV SRLQMQLHLR GLQNSASDLR GQLQQLRKLQ LQNQESVRAL 720
LKRTEAELSM RVSEAARRQE DPLQRQRTLV EEERLRYLND EELITQQLND LEKSVEKIQR 780
DVAHNHRLVP GPELEEKALV LKQLGETLTE LKAHFPGLQS KMRVVLRVEV EAVKFLKEEP 840
QRLDGLLKRC RGVTDTLAQI RRQVDEGMWP PPNNLLNQSP KKVAAETDFS KGLDFEIPPP 900
SPPLNLHELS GPAEGTPLTP KSTNPTKGLD ASSKRNTDKA VSVEAAERDW EEKRAALTQY 960
SAKDINRLLE ETQAELLKAI PDLDCASKTH PGPAPTPDHK PPKAPHGQKA APRTEPSGRR 1020
GSDELTVPRY RTEKPSKSPP PPPPRRSFPS SHGLTTTRTG EVVVTSKKDS VFIKKAESEE 1080
LEVQKPQVKL RRAVSEVVRP ASTPPIMASA IKDEDDEERI IAELESGGSS VPPMKVVTPG 1140
ASRLKAAQGP AGSPDKGKHG KQRTEYMRIQ AQQQVRVDFQ APRPLEGHTP RLCYMPLS 1198 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; ISA:MGI.
 GO:0007162; P:negative regulation of cell adhesion; IDA:MGI.
 GO:0030334; P:regulation of cell migration; IEA:InterPro.
 GO:0061001; P:regulation of dendritic spine morphogenesis; IEA:InterPro.
 GO:0034446; P:substrate adhesion-dependent cell spreading; IEA:InterPro. 
Interpro
 IPR026727; Srcin1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS