CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018140
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tubulin-specific chaperone C 
Protein Synonyms/Alias
 Tubulin-folding cofactor C; CFC 
Gene Name
 Tbcc 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
55DQEVEEEKSGFFAAAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Tubulin-folding protein; involved in the final step of the tubulin folding pathway (By similarity). 
Sequence Annotation
 DOMAIN 163 318 C-CAP/cofactor C-like.  
Keyword
 Chaperone; Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 341 AA 
Protein Sequence
MEGVDCSMAL ADAAAGSPRD LSLVPERLQR REQERQIEVE RRKQKRQDQE VEEEKSGFFA 60
AAFARERAAV EELLRGEASA ERLEEAANRL QGLRKLLNDS VLFLAAYDLR QGQAALAQLQ 120
AVLTERRQEL QPKKRFAFKA RKKDAAGTAQ VDAAPVTSAA PSPPVTKEEE GAPGASWACG 180
FSNLESQDLE KRAEELHQRD VLLSDLTNCT VKLCGNPNTL RLAKARGCKV LCGPVTTSVF 240
LEDCRDCVLA VACQQLRVHT TKDTRVFLQV TSRAIVEDCS GIQFAPYTWS YPGIDKDFQD 300
SGLDRSKNNW DQVDDFNWLA RNVASPNWSI LPEEERDIQW D 341 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0032391; C:photoreceptor connecting cilium; ISS:UniProtKB.
 GO:0003924; F:GTPase activity; ISS:UniProtKB.
 GO:0000902; P:cell morphogenesis; IEA:InterPro.
 GO:0007023; P:post-chaperonin tubulin folding pathway; ISS:UniProtKB. 
Interpro
 IPR017901; C-CAP_CF_C-like.
 IPR016098; CAP/MinC_C.
 IPR006599; CARP_motif.
 IPR012945; Tubulin-bd_cofactor_C. 
Pfam
 PF07986; TBCC 
SMART
 SM00673; CARP 
PROSITE
 PS51329; C_CAP_COFACTOR_C 
PRINTS