CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024814
UniProt Accession
Genbank Protein ID
 U51277 
Genbank Nucleotide ID
Protein Name
 Bcl-x-gamma 
Protein Synonyms/Alias
  
Gene Name
 Bcl2l1 
Gene Synonyms/Alias
 Bcl2l 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
87VIPMAAVKQALREAGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 235 AA 
Protein Sequence
MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEE TEAERETPSA INGNPSWHLA 60
DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR YRRAFSDLTS QLHITPGTAY 120
QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL CVESVDKEMQ VLVSRIASWM ATYLNDHLEP 180
WIQENGGWGV SGGTPLRSVF RRLVQVPGVA EHVCDPSLWE VETEGSEVQG PPQLL 235 
Gene Ontology
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0031966; C:mitochondrial membrane; IDA:MGI.
 GO:0071839; P:apoptotic process in bone marrow; IMP:MGI.
 GO:0008283; P:cell proliferation; IDA:MGI.
 GO:0060154; P:cellular process regulating host cell cycle in response to virus; IMP:MGI.
 GO:0071312; P:cellular response to alkaloid; IDA:MGI.
 GO:0071230; P:cellular response to amino acid stimulus; IMP:MGI.
 GO:0071480; P:cellular response to gamma radiation; IMP:MGI.
 GO:0009566; P:fertilization; IGI:MGI.
 GO:0007281; P:germ cell development; IMP:MGI.
 GO:0040007; P:growth; IMP:MGI.
 GO:0097284; P:hepatocyte apoptotic process; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:MGI.
 GO:0008584; P:male gonad development; IMP:MGI.
 GO:0043524; P:negative regulation of neuron apoptotic process; IDA:MGI.
 GO:0051402; P:neuron apoptotic process; IMP:MGI.
 GO:0001541; P:ovarian follicle development; IMP:MGI.
 GO:0043065; P:positive regulation of apoptotic process; IDA:MGI.
 GO:0008284; P:positive regulation of cell proliferation; IDA:MGI.
 GO:0001836; P:release of cytochrome c from mitochondria; IGI:MGI.
 GO:0046898; P:response to cycloheximide; IDA:MGI.
 GO:0034097; P:response to cytokine stimulus; ISO:MGI.
 GO:0007283; P:spermatogenesis; IGI:MGI. 
Interpro
 IPR013279; Apop_reg_BclX.
 IPR002475; Bcl2-like.
 IPR020717; Bcl2_BH1_motif_CS.
 IPR020728; Bcl2_BH3_motif_CS.
 IPR003093; Bcl2_BH4.
 IPR020731; Bcl2_BH4_motif_CS.
 IPR026298; Blc2_fam. 
Pfam
 PF00452; Bcl-2
 PF02180; BH4 
SMART
 SM00265; BH4 
PROSITE
 PS50062; BCL2_FAMILY
 PS01080; BH1
 PS01259; BH3
 PS01260; BH4_1
 PS50063; BH4_2 
PRINTS
 PR01864; APOPREGBCLX.
 PR01862; BCL2FAMILY.