CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014778
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome b-c1 complex subunit 1, mitochondrial 
Protein Synonyms/Alias
 Complex III subunit 1; Core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1 
Gene Name
 Uqcrc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
85GSRYETEKNNGAGYFacetylation[1]
99FLEHLAFKGTKNRPGacetylation[1]
111RPGNALEKEVESIGAacetylation[1]
134EHTAYLIKALSKDLPacetylation[1]
138YLIKALSKDLPKVVEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 (By similarity). 
Sequence Annotation
 MOD_RES 111 111 N6-acetyllysine (By similarity).
 MOD_RES 138 138 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Direct protein sequencing; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transit peptide; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 480 AA 
Protein Sequence
MAASAVCRAA CSGTQALLRT CRSPALLRLP ALRGTATFVQ ALQSVPETQV SVLDNGLRVA 60
SEQSSHPTCT VGVWIDVGSR YETEKNNGAG YFLEHLAFKG TKNRPGNALE KEVESIGAHL 120
NAYSTREHTA YLIKALSKDL PKVVELLADI VQNISLEDSQ IEKERDVILR EMQENDASMQ 180
NVVFDYLHAT AFQGTPLAQA VEGPSENVRR LSRTDLTDYL SRHYKAPRMV LAAAGGVKHQ 240
QLLDLAQDHF SSVSQVYEED AVPSITPCRF TGSEIRHRDD ALPLAHVAIA VEGPGWANPD 300
NVALQVANAI IGHYDCTYGG GVHLSSPLAS VAVANKLCQS FQTFNISYSE TGLLGAHFVC 360
DAMSIDDMIF FLQGQWMRLC TSATESEVTR GKNILRNALI SHLDGTTPVC EDIGRSLLTY 420
GRRIPLAEWE SRIEEVDAQM VREVCSKYFY DQCPAVAGYG PIEQLSDYNR IRSGMFWLRF 480 
Gene Ontology
 GO:0005750; C:mitochondrial respiratory chain complex III; IDA:RGD.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0032403; F:protein complex binding; IDA:RGD.
 GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:Compara.
 GO:0014823; P:response to activity; IEP:RGD.
 GO:0043279; P:response to alkaloid; IEP:RGD. 
Interpro
 IPR011249; Metalloenz_LuxS/M16.
 IPR011237; Pept_M16_dom.
 IPR011765; Pept_M16_N.
 IPR007863; Peptidase_M16_C. 
Pfam
 PF00675; Peptidase_M16
 PF05193; Peptidase_M16_C 
SMART
  
PROSITE
  
PRINTS