UniProt Accession

 KEG1_MOUSE; Q9DCY0 

Genbank Protein ID

 AK002360; AK165515; BC010803 

Genbank Nucleotide ID

 BAB22039.1; BAE38231.1; AAH10803.1 

Protein Name

 Glycine N-acyltransferase-like protein Keg1 

Protein Synonyms/Alias

 Acyl-CoA:glycine N-acyltransferase protein Keg1; Kidney-expressed gene 1 protein 

Gene Name

 Keg1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
19	VLENSLRKHLPESLK	acetylation	[1]
43	QGNPFKLKTLVDKWP	acetylation	[2]
83	LVYSKDPKHCQEFLG	acetylation	[1, 2]
112	SSQSDLGKVIESLGA	acetylation	[2]
112	SSQSDLGKVIESLGA	ubiquitination	[3]
124	LGATNLGKVKHKQCF	acetylation	[2]
124	LGATNLGKVKHKQCF	ubiquitination	[3]
126	ATNLGKVKHKQCFLY	acetylation	[2]
128	NLGKVKHKQCFLYMV	acetylation	[2]
140	YMVCQTAKKLAPSLM	acetylation	[2]
150	APSLMDAKNLVVSRN	acetylation	[2]
150	APSLMDAKNLVVSRN	ubiquitination	[3]
158	NLVVSRNKLTPLDQQ	acetylation	[2]
158	NLVVSRNKLTPLDQQ	ubiquitination	[3]
194	GGNEKSQKFIERCIF	acetylation	[2]
235	RMGGTLPKYRRQSLI	acetylation	[2]
266	PMYAHVDKANFTVQR	acetylation	[2]

Reference

 [1] Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.
 Kim SC, Sprung R, Chen Y, Xu Y, Ball H, Pei J, Cheng T, Kho Y, Xiao H, Xiao L, Grishin NV, White M, Yang XJ, Zhao Y.
 Mol Cell. 2006 Aug;23(4):607-18. [PMID: 16916647]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). 

Sequence Annotation

 MOD_RES 19 19 N6-acetyllysine.
 MOD_RES 83 83 N6-acetyllysine.  

Keyword

 Acetylation; Acyltransferase; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Mitochondrion; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 295 AA 

Protein Sequence

Gene Ontology

 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
 GO:0005739; C:mitochondrion; IDA:UniProtKB.
 GO:0047961; F:glycine N-acyltransferase activity; IEA:EC. 

Interpro

 IPR016181; Acyl_CoA_acyltransferase.
 IPR010313; Glycine_N-acyltransferase.
 IPR013652; Glycine_N-acyltransferase_C.
 IPR015938; Glycine_N-acyltransferase_N. 

Pfam

 PF08444; Gly_acyl_tr_C
 PF06021; Gly_acyl_tr_N 

SMART

  

PROSITE

  

PRINTS