CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042206
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Malate dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 LOC100734239 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
73KDVIATDKEEVAFKDacetylation[1]
103MERKDLLKANVKIFKacetylation[1]
118SQGAALDKYAKKSVKacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; NAD; Oxidoreductase; Reference proteome; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 334 AA 
Protein Sequence
QSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIVLVL LDITPMMGVL DGVLMELQDC 60
ALPLLKDVIA TDKEEVAFKD LDVAVLVGSM PRREGMERKD LLKANVKIFK SQGAALDKYA 120
KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKSQIALK LGVTADDVKN 180
VIIWGNHSST QYPDVNHAKV KLHGKEVGVY EALKDDSWLK GDFITTVQQR GAAVIKARKL 240
SSAMSAAKAI ADHIRDIWFG TPEGEFVSMG VISDGNSYGI PDDLLYSFPV VIKNKTWKFV 300
EGLPINDFSR EKMDITAKEL AEEKETAFEF LSSA 334 
Gene Ontology
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006108; P:malate metabolic process; IEA:InterPro.
 GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. 
Interpro
 IPR001557; L-lactate/malate_DH.
 IPR022383; Lactate/malate_DH_C.
 IPR001236; Lactate/malate_DH_N.
 IPR015955; Lactate_DH/Glyco_Ohase_4_C.
 IPR001252; Malate_DH_AS.
 IPR011274; Malate_DH_NAD-dep_euk.
 IPR010945; Malate_DH_type2.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02866; Ldh_1_C
 PF00056; Ldh_1_N 
SMART
  
PROSITE
 PS00068; MDH 
PRINTS