CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020791
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinesin-like protein KIF12 
Protein Synonyms/Alias
  
Gene Name
 Kif12 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
368TTRPQGPKSPGVKPPubiquitination[1]
373GPKSPGVKPPQQVENubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 DOMAIN 22 288 Kinesin-motor.
 NP_BIND 104 111 ATP (By similarity).  
Keyword
 ATP-binding; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 642 AA 
Protein Sequence
MEERGSPDGD PARNLEQGPE GSETPIQVVL RVRPMSTVEL RRGEQSALHC SGTRTLQVSP 60
DVAFRFGAVL DGARTQEDVF RACGVKRLGE LALRGFSCTV FTFGQTGSGK TYTLTGPPPQ 120
GEGVPVPPSL AGIMQRTFTW LLDRVQHLDS PVTLRASYLE IYNEQVWDLL SLGSPRPLPV 180
RWTKARGFYV EQLRVVEFGS LEALMELLQM GLSRRRSSSH TLNQASSRSH ALLTLHISRP 240
TSQQVPPVDL GEPPVGGKLC FVDLAGSEKV AATGSQGQLM LEANSINRSL LALGHCISLL 300
LDPQRKQNHI PFRDSKLTKL LADSLGGRGV TLMVACVSPS AQCLPETLST LRYASRAQRI 360
TTRPQGPKSP GVKPPQQVEN ELLRLQEENR HLRFQLDQMH TTAPGAHGAR MAWAQRNLYG 420
MLQEFMLENE RLRKEMRQLR SSRDLARAEQ RVLAQQVHDL ERRLLSACPL PQQGSTPVCP 480
CRMVPAASCH ALPPLCYCHH FCPLCRVPLA HWTCPRRECH MPQVLEPEAP GHISQSVWPP 540
PWAPPPSPGS AKPPRERSQS DWTQTRVLAE MLMGEEVVPS APPLSAGPSN MPYGLRGGSG 600
IPNLTPRLET LTQQINSSLH LSQRQPQPSE DTQSPGQGLS SC 642 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.