| Tag | Content |
|---|
| CPLM ID | CPLM-004155 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Keratin, type I cytoskeletal 10 |
Protein Synonyms/Alias | Cytokeratin-10; CK-10; Keratin-10; K10 |
Gene Name | KRT10 |
Gene Synonyms/Alias | KPP |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 163 | RLASYLDKVRALEES | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | |
Sequence Annotation | REGION 1 145 Head.
REGION 146 456 Rod.
REGION 146 181 Coil 1A.
REGION 182 202 Linker 1.
REGION 203 294 Coil 1B.
REGION 295 317 Linker 12.
REGION 318 456 Coil 2.
REGION 457 584 Tail.
MOD_RES 16 16 Phosphoserine.
MOD_RES 42 42 Phosphoserine.
MOD_RES 56 56 Phosphoserine (By similarity). |
Keyword | 3D-structure; Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Ichthyosis; Intermediate filament; Keratin; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 584 AA |
Protein Sequence | MSVRYSSSKH YSSSRSGGGG GGGGCGGGGG VSSLRISSSK GSLGGGFSSG GFSGGSFSRG 60
SSGGGCFGGS SGGYGGLGGF GGGSFRGSYG SSSFGGSYGG IFGGGSFGGG SFGGGSFGGG 120
GFGGGGFGGG FGGGFGGDGG LLSGNEKVTM QNLNDRLASY LDKVRALEES NYELEGKIKE 180
WYEKHGNSHQ GEPRDYSKYY KTIDDLKNQI LNLTTDNANI LLQIDNARLA ADDFRLKYEN 240
EVALRQSVEA DINGLRRVLD ELTLTKADLE MQIESLTEEL AYLKKNHEEE MKDLRNVSTG 300
DVNVEMNAAP GVDLTQLLNN MRSQYEQLAE QNRKDAEAWF NEKSKELTTE IDNNIEQISS 360
YKSEITELRR NVQALEIELQ SQLALKQSLE ASLAETEGRY CVQLSQIQAQ ISALEEQLQQ 420
IRAETECQNT EYQQLLDIKI RLENEIQTYR SLLEGEGSSG GGGRGGGSFG GGYGGGSSGG 480
GSSGGGHGGG HGGSSGGGYG GGSSGGGSSG GGYGGGSSSG GHGGSSSGGY GGGSSGGGGG 540
GYGGGSSGGG SSSGGGYGGG SSSGGHKSSS SGSVGESSSK GPRY 584 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:UniProtKB. GO:0005882; C:intermediate filament; NAS:UniProtKB. GO:0045095; C:keratin filament; IEA:Compara. GO:0030280; F:structural constituent of epidermis; NAS:UniProtKB. GO:0071277; P:cellular response to calcium ion; IEA:Compara. GO:0030216; P:keratinocyte differentiation; IEP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |