| Tag | Content |
|---|
| CPLM ID | CPLM-002703 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor 1-alpha 1 |
Protein Synonyms/Alias | EF-1-alpha-1; 50 kDa female-specific protein |
Gene Name | Ef1alpha48D |
Gene Synonyms/Alias | EF1B; F1; CG8280 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 330 | GYVAGDSKANPPKGA | acetylation | [1] | | 392 | KTTEENPKFIKSGDA | acetylation | [1] | | 395 | EENPKFIKSGDAAIV | acetylation | [1] | | 444 | VIKAVNFKDASGGKV | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. |
Sequence Annotation | NP_BIND 14 21 GTP (By similarity).
NP_BIND 91 95 GTP (By similarity).
NP_BIND 153 156 GTP (By similarity).
MOD_RES 301 301 5-glutamyl glycerylphosphorylethanolamine
MOD_RES 374 374 5-glutamyl glycerylphosphorylethanolamine |
Keyword | Complete proteome; Cytoplasm; Direct protein sequencing; Elongation factor; GTP-binding; Nucleotide-binding; Phosphoprotein; Protein biosynthesis; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 463 AA |
Protein Sequence | MGKEKIHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAQEMG KGSFKYAWVL 60
DKLKAERERG ITIDIALWKF ETAKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGT 120
GEFEAGISKN GQTREHALLA FTLGVKQLIV GVNKMDSSEP PYSEARYEEI KKEVSSYIKK 180
IGYNPAAVAF VPISGWHGDN MLEPSTNMPW FKGWKVERKE GNADGKTLID ALDAILPPAR 240
PTDKALRLPL QDVYKIGGIG TVPVGRVETG VLKPGTVVVF APANITTEVK SVEMHHEALQ 300
EAVPGDNVGF NVKNVSVKEL RRGYVAGDSK ANPPKGAADF TAQVIVLNHP GQIANGYTPV 360
LDCHTAHIAC KFAEIKEKVD RRSGKTTEEN PKFIKSGDAA IVNLVPSKPL CVEAFQEFPP 420
LGRFAVRDMR QTVAVGVIKA VNFKDASGGK VTKAAEKATK GKK 463 |
Gene Ontology | GO:0005829; C:cytosol; ISS:FlyBase. GO:0005853; C:eukaryotic translation elongation factor 1 complex; ISS:FlyBase. GO:0005811; C:lipid particle; IDA:FlyBase. GO:0005875; C:microtubule associated complex; IDA:FlyBase. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0003746; F:translation elongation factor activity; ISS:FlyBase. GO:0008340; P:determination of adult lifespan; IMP:FlyBase. GO:0006184; P:GTP catabolic process; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |