| Tag | Content |
|---|
| CPLM ID | CPLM-004491 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Reduced growth phenotype protein 1 |
Protein Synonyms/Alias | |
Gene Name | RGP1 |
Gene Synonyms/Alias | YDR137W; YD9302.13 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 59 | EKLLTVDKAVEEKLE | ubiquitination | [1] | | 64 | VDKAVEEKLEQQAKV | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | The RIC1-RGP1 complex formed with RGP1 acts as a guanine nucleotide exchange factor (GEF), which activates YPT6 by exchanging bound GDP for free GTP. It is thereby required for efficient fusion of endosome-derived vesicles with the Golgi. The RIC1-RGP1 participates in the recycling of SNC1, presumably by mediating fusion of endosomal vesicles with the Golgi compartment. |
Sequence Annotation | MOD_RES 351 351 Phosphoserine.
MOD_RES 354 354 Phosphoserine.
MOD_RES 357 357 Phosphoserine.
MOD_RES 363 363 Phosphoserine.
MOD_RES 364 364 Phosphoserine.
MOD_RES 370 370 Phosphoserine. |
Keyword | Cell cycle; Cell division; Complete proteome; Golgi apparatus; Guanine-nucleotide releasing factor; Mitosis; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 663 AA |
Protein Sequence | MRAHRIDTFL IRENIKLEII HESNSYFGGE HISIAFRFKH LGSQHELFNY KEKLLTVDKA 60
VEEKLEQQAK VQDDGEGTME NQTWSLKSLL GAFKRTGEPE ESVDVDNMKM LNESKMLREK 120
IQKQMYFHQP VTLISGYVQI SGVFQYDSEV ISESKFKQDE VKMVGLDIVP GHTTNSVLAL 180
EDGEHFKGKR NLTNYLNSDY TNVTNGLLFS ESGSRGRTGT YNERTLMISN DTSIKTLPLL 240
LIPQTLLFSE ISLEPGEVRT FYFKSTKLPK DICPSYSSSK VASINYTLEV GADVLSDDNI 300
EKFSNRVPIT IAPYISSNAE QYTSRLDKPA IILKTGNIKE LKPRLFTRKV STASAVSFGR 360
RKSSIIDIDS PLEDNEFVKR VKKNFIELVE SNQNVSRDID ELIDLQMGVQ FGKDEDSSDP 420
EPNDSHFSNE MVTSAESSLR SDAVTKRRKS YSVRDNISNL EQKMWNDCSL VKSDENSNLL 480
PQLINLQNAY QINRNNETMA KVSLSAPFYK TTDDINLVIE LDPITTPLLK VTSLTVSLES 540
FEIINPKYKT EGKGIGSKPK GNSVYEKHFI CFDECKSVSV KLLPPRSPTN QITGQFKTDV 600
FQHKWMIGLK FVIIAKTESI TLDQFYEDKK GILFHSKENL EGEEFTCYVP IPILCTSEDF 660
MGW 663 |
Gene Ontology | GO:0000139; C:Golgi membrane; IPI:SGD. GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:SGD. GO:0034066; C:Ric1p-Rgp1p complex; IPI:SGD. GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. GO:0051301; P:cell division; IEA:UniProtKB-KW. GO:0007067; P:mitosis; IEA:UniProtKB-KW. GO:0042147; P:retrograde transport, endosome to Golgi; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |