CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036976
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptojanin-2 
Protein Synonyms/Alias
  
Gene Name
 SYNJ2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1387LNNTWLSKSSDPLDSubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1451 AA 
Protein Sequence
MALSKGLRLL GRLGAEGDCS VLLEARGRDD CLLFEAGTVA TLAPEEKEVI KGQYGKLTDA 60
YGCLGELRLK SGGTSLSFLV LVTGCTSVGR IPDAEIYKIT ATDFYPLQEE AKEEERLIAL 120
KKILSSGVFY FSWPNDGSRF DLTVRTQKQG DDSSEWGNSF FWNQLLHVPL RQHQVSCCDW 180
LLKIICGVVT IRTVYASHKQ AKACLVSRVS CERTGTRFHT RGVNDDGHVS NFVETEQMIY 240
MDDGVSSFVQ IRGSVPLFWE QPGLQVGSHH LRLHRGLEAN APAFDRHMVL LKEQYGQQVV 300
VNLLGSRGGE EVLNRAFKKL LWASCHAGDT PMINFDFHQF AKGGKLEKLE TLLRPQLKLH 360
WEDFDVFTKG ENVSPRFQKG TLRMNCLDCL DRTNTVQSFI ALEVLHLQLK TLGLSSKPIV 420
DRFVESFKAM WSLNGHSLSK VFTGSRALEG KAKVGKLKDG ARSMSRTIQS NFFDGVKQEA 480
IKLLLVGDVY GEEVADKGGM LLDSTALLVT PRILKAMTER QSEFTNFKRI RIAMGTWNVN 540
GGKQFRSNVL RTAELTDWLL DSPQLSGATD SQDDSSPADI FAVGFEEMVE LSAGNIVNAS 600
TTNKKMWGEQ LQKAISRSHR YILLTSAQLV GVCLYIFVRP YHVPFIRDVA IDTVKTGMGG 660
KAGNKGAVGI RFQFHSTSFC FICSHLTAGQ SQVKERNEDY KEITQKLCFP MGRNVFSHDY 720
VFWCGDFNYR IDLTYEEVFY FVKRQDWKKL LEFDQLQLQK SSGKIFKDFH EGAINFGPTY 780
KYDVGSAAYD TSDKCRTPAW TDRVLWWRKK HPFDKTAGEL NLLDSDLDVD TKVRHTWSPG 840
ALQYYGRAEL QASDHRPVLA IVEVEVQEVD VGARERVFQE VSSFQGPLDA TVVVNLQSPT 900
LEEKNEFPED LRTELMQTLG SYGTIVLVRI NQGQMLVTFA DSHSALSVLD VDGMKVKGRA 960
VKIRPKTKDW LKGLREEIIR KRDSMAPVSP TANSCLLEEN FDFTSLDYES EGDILEDDED 1020
YLVDEFNQPG VSDSELGGDD LSDVPGPTAL APPSKSPALT KKKQHPTYKA GLMVKKSASD 1080
ASISSGTHGQ YSILQTARLL PGAPQQPPKA RTGISKPYNV KQIKTTNAQE AEAAIRCLLE 1140
ARGGASEEAL SAVAPRDLEA SSEPEPTPGA AKPETPQAPP LLPRRPPPRV PAIKKPTLRR 1200
TGKPLSPEEQ FEQQTVHFTI GPPETSVEAP PVVTAPRVPP VPKPRTFQPG KAAERPSHRK 1260
PASDEAPPGA GASVPPPLEA PPLVPKVPPR RKKSAPAAFH LQVLQSNSQL LQGLTYNSSD 1320
SPSGHPPAAG TVFPQGDFLS TSSATSPDSD GTKAMKPEAA PLLGDYQDPF WNLLHHPKLL 1380
NNTWLSKSSD PLDSGTRSPK RDPIDPVSAG ASAAKAELPP DHEHKTLGHW VTISDQEKRT 1440
ALQVFDPLAK T 1451 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0042578; F:phosphoric ester hydrolase activity; IEA:InterPro.
 GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro. 
Interpro
 IPR015047; DUF1866.
 IPR005135; Endo/exonuclease/phosphatase.
 IPR000300; IPPc.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR002013; Syja_N. 
Pfam
 PF08952; DUF1866
 PF03372; Exo_endo_phos
 PF02383; Syja_N 
SMART
 SM00128; IPPc 
PROSITE
 PS50102; RRM
 PS50275; SAC 
PRINTS