CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022554
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosome-binding protein 1 
Protein Synonyms/Alias
 180 kDa ribosome receptor homolog; RRp; ES/130-related protein; Ribosome receptor protein 
Gene Name
 RRBP1 
Gene Synonyms/Alias
 KIAA1398 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
166SIQVLTSKAAILETAubiquitination[1]
588EGSPNQGKKADAAANubiquitination[1]
589GSPNQGKKADAAANQubiquitination[1]
598DAAANQGKKTESASVubiquitination[1]
1238QSQLDAAKSEAQKQSubiquitination[1]
1347TEEASQLKERLEKEKubiquitination[1]
1372TRLQELLKTTQEQLAubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
 Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane (By similarity). 
Sequence Annotation
 REPEAT 197 206 1.
 REPEAT 207 216 2.
 REPEAT 217 226 3.
 REPEAT 227 236 4.
 REPEAT 237 246 5.
 REPEAT 247 256 6.
 REPEAT 257 266 7.
 REPEAT 267 276 8.
 REPEAT 277 286 9.
 REPEAT 287 296 10.
 REPEAT 297 306 11.
 REPEAT 307 316 12.
 REPEAT 317 326 13.
 REPEAT 327 336 14.
 REPEAT 337 346 15.
 REPEAT 347 356 16.
 REPEAT 357 366 17.
 REPEAT 367 376 18.
 REPEAT 377 386 19.
 REPEAT 387 396 20.
 REPEAT 397 406 21.
 REPEAT 407 416 22.
 REPEAT 417 426 23.
 REPEAT 427 436 24.
 REPEAT 437 446 25.
 REPEAT 447 456 26.
 REPEAT 457 466 27.
 REPEAT 467 476 28.
 REPEAT 477 486 29.
 REPEAT 487 496 30.
 REPEAT 497 506 31.
 REPEAT 507 516 32.
 REPEAT 517 526 33.
 REPEAT 527 534 34; approximate.
 REPEAT 535 544 35.
 REPEAT 545 554 36; approximate.
 REPEAT 555 564 37.
 REPEAT 565 574 38.
 REPEAT 575 584 39; approximate.
 REPEAT 585 594 40.
 REPEAT 595 604 41.
 REGION 197 604 41 X 10 AA approximate tandem repeats of
 MOD_RES 225 225 Phosphothreonine.
 MOD_RES 235 235 Phosphothreonine.
 MOD_RES 245 245 Phosphothreonine.
 MOD_RES 255 255 Phosphothreonine.
 MOD_RES 533 533 Phosphoserine.
 MOD_RES 583 583 Phosphoserine.
 MOD_RES 615 615 Phosphoserine.
 MOD_RES 978 978 Phosphoserine.
 MOD_RES 1276 1276 Phosphoserine.
 MOD_RES 1277 1277 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Endoplasmic reticulum; Membrane; Phosphoprotein; Polymorphism; Protein transport; Reference proteome; Repeat; Translocation; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1410 AA 
Protein Sequence
MDIYDTQTLG VVVFGGFMVV SAIGIFLVST FSMKETSYEE ALANQRKEMA KTHHQKVEKK 60
KKEKTVEKKG KTKKKEEKPN GKIPDHDPAP NVTVLLREPV RAPAVAVAPT PVQPPIIVAP 120
VATVPAMPQE KLASSPKDKK KKEKKVAKVE PAVSSVVNSI QVLTSKAAIL ETAPKEVPMV 180
VVPPVGAKGN TPATGTTQGK KAEGTQNQSK KAEGAPNQGR KAEGTPNQGK KTEGTPNQGK 240
KAEGTPNQGK KAEGTPNQGK KAEGAQNQGK KVDTTPNQGK KVEGAPTQGR KAEGAQNQAK 300
KVEGAQNQGK KAEGAQNQGK KGEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK 360
KAEGAQNQGK KAEGAQNQGK KSEGAQNQGK KVEGAQNQGK KAEGAQNQGK KAEGAQNQGK 420
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KAEGAQNQGK KVEGAQNQGK 480
KAEGAQNQGK KAEGAQNQGK KAEGAQNQGQ KGEGAQNQGK KTEGAQGKKA ERSPNQGKKG 540
EGAPIQGKKA DSVANQGTKV EGITNQGKKA EGSPSEGKKA EGSPNQGKKA DAAANQGKKT 600
ESASVQGRNT DVAQSPEAPK QEAPAKKKSG SKKKGPPDAD GPLYLPYKTL VSTVGSMVFN 660
EGEAQRLIEI LSEKAGIIQD TWHKATQKGD PVAILKRQLE EKEKLLATEQ EDAAVAKSKL 720
RELNKEMAAE KAKAAAGEAK VKKQLVAREQ EITAVQARMQ ASYREHVKEV QQLQGKIRTL 780
QEQLENGPNT QLARLQQENS ILRDALNQAT SQVESKQNAE LAKLRQELSK VSKELVEKSE 840
AVRQDEQQRK ALEAKAAAFE KQVLQLQASH RESEEALQKR LDEVSRELCH TQSSHASLRA 900
DAEKAQEQQQ QMAELHSKLQ SSEAEVRSKC EELSGLHGQL QEARAENSQL TERIRSIEAL 960
LEAGQARDAQ DVQASQAEAD QQQTRLKELE SQVSGLEKEA IELREAVEQQ KVKNNDLREK 1020
NWKAMEALAT AEQACKEKLL SLTQAKEESE KQLCLIEAQT MEALLALLPE LSVLAQQNYT 1080
EWLQDLKEKG PTLLKHPPAP AEPSSDLASK LREAEETQST LQAECDQYRS ILAETEGMLR 1140
DLQKSVEEEE QVWRAKVGAA EEELQKSRVT VKHLEEIVEK LKGELESSDQ VREHTSHLEA 1200
ELEKHMAAAS AECQNYAKEV AGLRQLLLES QSQLDAAKSE AQKQSDELAL VRQQLSEMKS 1260
HVEDGDIAGA PASSPEAPPA EQDPVQLKTQ LEWTEAILED EQTQRQKLTA EFEEAQTSAC 1320
RLQEELEKLR TAGPLESSET EEASQLKERL EKEKKLTSDL GRAATRLQEL LKTTQEQLAR 1380
EKDTVKKLQE QLEKAEDGSS SKEGTSV 1407 
Gene Ontology
 GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:UniProtKB.
 GO:0005840; C:ribosome; TAS:ProtInc.
 GO:0004872; F:receptor activity; TAS:ProtInc.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0007165; P:signal transduction; NAS:UniProtKB.
 GO:0006412; P:translation; TAS:ProtInc. 
Interpro
 IPR007794; Rib_rcpt_KP. 
Pfam
 PF05104; Rib_recp_KP_reg 
SMART
  
PROSITE
  
PRINTS