CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036132
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Rho-related BTB domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 RHOBTB3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
169LDIVDLLKKAKFHHSubiquitination[1, 2, 3, 4, 5]
223WPSNMYLKQLAEYRKubiquitination[1, 4, 5]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 242 AA 
Protein Sequence
MPKRAVLFTD RQPIQFLKIN CLRNCKTYQA RKPLWFYNTS LKFFLNKPML ADVVFEIQGT 60
TVPAHRAILV ARCEVMAAMF NGNYMEAKSV LIPVYGVSKE TFLSFLEYLY TDSCCPAGIF 120
QAMCLLICAE MYQVSRLQHI CELFIITQLQ SMPSRELASM NLDIVDLLKK AKFHHSDCLS 180
TWLLHFIATN YLIFSQKPEF QDLSVEERSF VEKHRWPSNM YLKQLAEYRK YIHSRKCRCL 240
VM 242 
Gene Ontology
  
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ. 
Pfam
 PF00651; BTB 
SMART
 SM00225; BTB 
PROSITE
 PS50097; BTB 
PRINTS