CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016030
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrosomal protein of 170 kDa protein B 
Protein Synonyms/Alias
 Centrosomal protein 170B; Cep170B 
Gene Name
 Cep170b 
Gene Synonyms/Alias
 Kiaa0284 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1320RLSQTLVKDVAILARubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Plays a role in microtubule organization (By similarity). 
Sequence Annotation
 DOMAIN 23 73 FHA.
 MOD_RES 360 360 Phosphoserine.
 MOD_RES 595 595 Phosphoserine (By similarity).
 MOD_RES 653 653 Phosphoserine (By similarity).
 MOD_RES 744 744 Phosphoserine (By similarity).
 MOD_RES 746 746 Phosphoserine (By similarity).
 MOD_RES 749 749 Phosphoserine (By similarity).
 MOD_RES 751 751 Phosphoserine (By similarity).
 MOD_RES 882 882 Phosphoserine.
 MOD_RES 965 965 Phosphoserine.
 MOD_RES 968 968 Phosphothreonine.
 MOD_RES 971 971 Phosphothreonine.
 MOD_RES 978 978 Phosphoserine.
 MOD_RES 981 981 Phosphoserine (By similarity).
 MOD_RES 1122 1122 Phosphoserine (By similarity).
 MOD_RES 1289 1289 Phosphothreonine (By similarity).
 MOD_RES 1341 1341 Phosphoserine.
 MOD_RES 1530 1530 Phosphoserine (By similarity).
 MOD_RES 1533 1533 Phosphoserine (By similarity).
 CROSSLNK 289 289 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Isopeptide bond; Microtubule; Phosphoprotein; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1574 AA 
Protein Sequence
MSVTSWFLVS SSGTRHRLPR ELIFVGRDEC ELMLQSRSVD KQHAVINYDQ DRDEHWVKDL 60
GSLNGTFVND VRIPDQKYIT LKLNDVIRFG YDSNMYVLER VQHRVPEEAL KHEKYTSQLQ 120
VSVKVSAPKR GDALPDHTPY CESSQPRPEK GDRRHGAEAV AYRTPLYGQP SWWGEDDSGA 180
PSEDRHQEEP YSERPKDLAQ QNGELDSCRA PAEPPDYSFR REPSYFEIPT KETPQPPRLP 240
EVPTQEVPTK DQEAGVGGTA PVVQSHASFT IEFDDCSPGK VKIKDHITKF SLRQRRAPSK 300
ETTPVETVSA ETKVADWLVQ NDPSLLRRDG PGDDRHSTKS DLPVHTRTLK GHKHEDGTQS 360
DSEDPLAKTA SVSGASAEAS GEQVRLQRQI KRDPQELLHN QQAFVIEFFD GDTPRKKRSQ 420
SFTHTPPADP KADKRRGPGT SDRDRPGVSV RATGSSSGPQ RASSLKREKT EERLGNTSPV 480
PRASTRSFGS VGRRSRLAQD FMAQCMRDSS PATRPAPEKT PPVLPAPLTP RGASPVTPST 540
TPPPPTDPQL TKARKQEEDD SLSDAGTYTI ETEAQDQEVE EARRMIDQVF GVFESPELSR 600
VSSATFRPVI RGDKDESSDG GMAQRMALLQ EFASRAPGMA PQMEQQSLLV PGSPGGQKWV 660
SRWASLADSY SDAGLPEDGP GRRTGEPEGP LPVRTRRLLP QLPSGRADSP AGLEAARRNG 720
PGPPELGSEP ANCLIGQEDL DPDSLSDASG SDGGRGPEPG TERQEDLAWV RGRRSPRAPG 780
ELVPTSFFIG DQNGEATFPK KSFVGPGEVD GPGRVVQTSP SARDGLYVSS NGRMVIQLRS 840
GRSPEPDPAP PKETLTFARQ ESFTKEPTSG PPAPGKLPHI SSHPLLQDLA AARASRLDFH 900
AQDTHLILKE TETALAALEA RLRSKSADEC DGGSTPRPPE DSLSGDSDVD TASTISLLSG 960
KNGPSPTTPQ TPGPQKESPL SPPTVPDPGG ATPGSARERM SERQHRPTPA DLGPGDTSRR 1020
AAMRRGHGSR GSLDWPEEER GSGLAHLPSS NHETPEATLA GRQGPRRKPA APPPSPAARE 1080
EQSRSSATAQ KVQQALTRSN SLSTPRPTRA SRLRRARLGD ASDTEAVDGE RGTAANPEPA 1140
NRAAPEQAKK LTRLDILAMP RKRAGSFTGP SDSETAPART GFSGRSAELY STSRKPTIAE 1200
ARAAAKKAAA TAANTGPRQP FSRARPGSAR YSSNTRRRQQ GSDYTSTSEE EYGSHHSSPK 1260
HTRSHASTAT QTPRGSSSTR ARSQGPRDTD DDEEEPDPYG FIVQTAEIAE IARLSQTLVK 1320
DVAILAREIH DVAGDGDSLG SPGPTRSPSL GNVPNTPAST ISAREELVQR IPEASLNFQK 1380
VPPGSMNSHN LDQNMNDSRD DALTNKTRPR NREEVIFDNL MLNPVSQLSH AIRENTEHLA 1440
EKMKVLFQNT GRAWEDLEAR INSENEVPIL KTSNKEISSI LKELRRVQKQ LEVINAIVDP 1500
SLNLDLLMGN RAPSGSGQPG LGKARPAAQS STSPASVDTL LPALPLRSFP QRANCGPPGL 1560
PEPAFLPDAE RFLI 1574 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW. 
Interpro
 IPR000253; FHA_dom.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF00498; FHA 
SMART
 SM00240; FHA 
PROSITE
 PS50006; FHA_DOMAIN 
PRINTS