| Tag | Content |
|---|
| CPLM ID | CPLM-006231 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mitochondrial escape protein 2 |
Protein Synonyms/Alias | Protein RNA12 |
Gene Name | YME2 |
Gene Synonyms/Alias | PRP12; RNA12; YMR302C; YM9952.04C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 129 | PIYGLELKSTIPVKR | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA. |
Sequence Annotation | DOMAIN 198 272 RRM. |
Keyword | Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; mRNA processing; Reference proteome; RNA-binding; Transit peptide; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 850 AA |
Protein Sequence | MLLVRTTSLN VSRMPVPCLA RGIGILKGKY RLANLMNAQP SVRHVSSEIQ QKDQQAGESN 60
TATDTGVIHK SDEETLIYFD NVYARTTSVW NPTLWYNLLL RNQSRDAVRE KIRNLASPPN 120
NPIYGLELKS TIPVKRDGGV FATFVVPPKY TKAQVNSLIQ QNTARESSKN LLSYFTRASA 180
FPVKGSPWIE DLRRLPSTTI VIKFQGPALT EEEIYSLFRR YGTIIDIFPP TAANNNVAKV 240
RYRSFRGAIS AKNCVSGIEI HNTVLHIQYE NIRRGHLVSN FFTNHTRIAI PVLFALLSIF 300
AVLVFDPIRE FSIEQKITHK YSLSWDNKFW KQLKTLTSST MTSIKYYWGG PDDNHQRKHL 360
WEERIEKVND LKMWLEENNN TFVVIRGPRG SGKHDLVMQH TLQNRANVLY LDCDKLIKSR 420
TDPMFLKNAA SQLGYFPIFP WIDSVTGVLD LTVQGLTGQK TGLSETKESR FRNMLTTSLM 480
SIRRIALKNY KAFVSTGDGT VNVKEEDYLQ QHPEAKPVIV IDRFEGKSEI NGFVYKELSD 540
WAAMLVQMNI AHVIFLTETV ASNQRLSESL PNQVFKNLIL SDASKENSRN YVLSQLEDYL 600
YYNKKSKGEN VKEPESEKET AENNDSDSEA DTSVKKAEVI LNEKELQEID ASLEPLGGRM 660
LDLQAFVRRV KSGEEPSEAV DKMIEQASEQ ITQMFLSDKI DSNKSAQAWE LIELLSANPV 720
IPFHEIVNKP LFKAAPETGI MELENNGLIT VSRDRGVLQE IRPAKPLYRA AFTYLINDPE 780
LAKVLKTRYL LKVVGFETGR IKKWEEELKP LGKVPDQKLF KTRLDYLSGK INASNAVITK 840
CEEEIKNLSK 850 |
Gene Ontology | GO:0031305; C:integral to mitochondrial inner membrane; IDA:SGD. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0000002; P:mitochondrial genome maintenance; IMP:SGD. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |