CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036524
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RhoGAP19D, isoform B 
Protein Synonyms/Alias
  
Gene Name
 RhoGAP19D 
Gene Synonyms/Alias
 CG1412; Dmel_CG1412 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
749SSSFDEGKPMRRISYacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2109 AA 
Protein Sequence
MLQNSNGAAA AHSAASAVAT PAAAASAAAA AAAAAVAAAA NNAALAASSI QPKLIVIRRR 60
PNQGFGFTLR HFIAYPPEDD QASSSASGLV SGSATAATAA SVSTNWPQEA SSAAGSNSGS 120
SSSVGVAGIT GLEPTSPTSL PPYQVKAMET IFIKEVQANG PAHYANLQTG DRVLMVNNQP 180
IAGIAYSTIV SMIKQTPAVL TLHVVPKECD VLQMHYTSIA HTPESNRLTM STHSPSLLAN 240
GSHKTTFPAA AAVAAPPHQH QQQQQQLISY PAVAAVTTST PAGSPQSQSQ SQSHSHPNTH 300
HAPSLHGGSR SGSITSTASG GITVLSQPFY PQQQQQQQQQ QQHRHPALTG GSSSIDFGDM 360
AHGLRQHQQQ QQHLYQQQQQ HHQFMRANQP PNLTVLSASS ATNTPTPTAR QPKSATSHNQ 420
ALYAVGAGPS SAAGSGSGSL SGGSENSDLM IRLRESIKQK EEFLKSPVPA SMSSASSING 480
NQAQSSSPAQ QQHLQQHQQH FFPSHTPPGG VQVVVPPPRS RHQVMLKQQQ QQQQQHQQHH 540
VLGYDMYHSG GKLVQRSSTA PGSVCHQHQQ QQQHHLYHQQ QHQQLQQTQH RQVMINNNAK 600
YAKDLDYFET LQETGVTNKV FERKLVSHMS KGFDPFKPLS INTSALESSA STSSTSATTT 660
VKKQSVLYES LQQHPLAKYH QTQQQTTTTT TVDGQTSSRM ELHKATLANA TIDPVPVGSS 720
TAIVDSASGS GNVVRRYKPL SSSSFDEGKP MRRISYLRAT NNETDFNAEA AAGGDAAATG 780
ASGPASASAA SSAPGPTPSS APAPAPAPAP LPISIPIPVA AVVEPQKTKS LVEEHPDPTY 840
DVIGGTGGGH EFIETPNGLE DVRLSAHGSR RASMSSDMRS SIHIDAELNG KYVPNELEAF 900
ETEIEIKSSC INGKRMSEYR SWRQVKLEIK GDLLRIYSGR HAKSEHNVIE LDIRNFKFFD 960
ESMDKKKYLI RMQSKPSPSG AHLASLGNEL NLDEGHDKLL TSSGSSSANE PAANAASALT 1020
ASTSSSTCSS GPYTEILFKT KSSNEMKRLF GLLQWKDSLN YDDNEHQPQG KQLAEPQKTV 1080
ASASYLDDVQ GGASAADSSP LSSHSGGIAD ASGSHHVSAL PAAAAIVAAT SDSISPVMKA 1140
RKSSSHKHIP DKDLGSPKSK NWKDLLFRRG GSGSGGVSHH DLASPSACAA KQIGSIGVPL 1200
RSCPMSKVNA YVPHLVEVCT NIVETKGLGV VGIYRIPGNK AAISELSELV NTKDFQFESC 1260
ASDDRWEDVN VVSSLLKLFI RSLPDALMPA SYYINFIEAD KKFGLERIVL LREIVESLPR 1320
HPYETMKHLI RHLCRVSGNC DVNRMEPKNL AIIFGPSIIR TPNDTLETAV KDMKHQCRIV 1380
ELLVTQYDYF FEGGSLPDIA EVSGGTAAVS AAQPQQQTQE DQTSMLLHNL SKIERITERE 1440
TTRTSRFMPQ LRRKTHGKRS AVNSDTYSGE SVLSLDYAKA SASASASASS TASTSSSSTL 1500
HSGGKASASS SSSSTTKFSS SSSSACSTTA VAISSSISAT SSKLLSANFK KRSTGGFLGS 1560
RSSHQTRKAS LDEKDSGQSS GSLGHSLGVG INLAKEQQRS SVDISILLTD DDSSSRLSDT 1620
GSMSLTTITD TLDSKLRNLR SGSESNDENG SPEFPKNRRH TLGQPLHMHS ENIPYADESP 1680
ERLFHQFCNP LETAPLSLHL SRSCTATNTI GGDEKPSKQS GGVAPLPPSL LKAAHKLQHS 1740
ATVPIHQGSS TAPTSGAATP VGTPTGSGGA GAIPSRSSSS SVTTLTKSIQ PRFSNYLSYE 1800
RGNAAAGGAE RVVGSAGGAA SDDDSEGSTT SDPKEKLLLG ERPSPSFFIE RYNKKRRDHR 1860
LFRSASFNCR NYSTRHITAQ TSGGVAAGVS GGVAGAVAVG VACCQALSTT GLTKDEKTDM 1920
NLTKKRQIQN KQNRSIKRRH TVGGPHDYSA SNGGCSNHSH GHDLAAINYN HHNRHHQQQL 1980
LKLGSATSGG GGSGAAAAET TTTTTTTTTV LRRLGTGQAG AEASVALPAS SSGSSSNNNN 2040
SPQSDGSNGN GGGVAGVASN APPTGVGVGG NNSSGSSSNS SSTSTTPAGN GDQVLEVGIR 2100
IKNISRGRF 2109 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0007480; P:imaginal disc-derived leg morphogenesis; IMP:FlyBase.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR001478; PDZ.
 IPR008936; Rho_GTPase_activation_prot.
 IPR000198; RhoGAP_dom. 
Pfam
 PF00595; PDZ
 PF00620; RhoGAP 
SMART
 SM00228; PDZ
 SM00324; RhoGAP 
PROSITE
 PS50106; PDZ
 PS50238; RHOGAP 
PRINTS