UniProt Accession

 CRIP1_RAT; P63255; P04006 

Genbank Protein ID

  

Genbank Nucleotide ID

  

Protein Name

 Cysteine-rich protein 1 

Protein Synonyms/Alias

 CRP-1; Cysteine-rich intestinal protein; CRIP 

Gene Name

 Crip1 

Gene Synonyms/Alias

 Crip 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
9	PKCPKCDKEVYFAER	acetylation	[1]
22	ERVTSLGKDWHRPCL	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. 

Sequence Annotation

 DOMAIN 2 63 LIM zinc-binding.
 MOD_RES 9 9 N6-acetyllysine (By similarity).  

Keyword

 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; LIM domain; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 77 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0003680; F:AT DNA binding; ISS:UniProtKB.
 GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
 GO:0042277; F:peptide binding; ISS:UniProtKB.
 GO:0008270; F:zinc ion binding; ISS:UniProtKB.
 GO:0071236; P:cellular response to antibiotic; ISS:UniProtKB.
 GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.
 GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; ISS:UniProtKB.
 GO:0010043; P:response to zinc ion; ISS:UniProtKB. 

Interpro

 IPR001781; Znf_LIM. 

Pfam

 PF00412; LIM 

SMART

 SM00132; LIM 

PROSITE

 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 

PRINTS