| Tag | Content |
|---|
| CPLM ID | CPLM-013039 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 2B |
Protein Synonyms/Alias | |
Gene Name | Tbc1d2b |
Gene Synonyms/Alias | Kiaa1055 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 43 | RLCGYLQKLSGKGPL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act as a GTPase-activating protein (By similarity). |
Sequence Annotation | DOMAIN 34 139 PH.
DOMAIN 664 858 Rab-GAP TBC.
MOD_RES 155 155 Phosphoserine.
MOD_RES 513 513 Phosphoserine.
MOD_RES 959 959 Phosphoserine. |
Keyword | Coiled coil; Complete proteome; GTPase activation; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 965 AA |
Protein Sequence | MPGAGDGVEE SCSGGEGAVP GTGSEAGAVA GREPSRLCGY LQKLSGKGPL RGYRSRWFVF 60
DSRRCYLYYF KSPQDALPLG HLDIADACFS YQGRDEAAEP GADPPTHFQV HSAGAVTVLK 120
APNRELMTYW LQELQQKRWE YCNSLDMMKW DSRTSPTPGD FPKGLVARDT TDIISQHPNP 180
SAEKARTVLA VEAAPGELVG DRAAHQPAPG HPNPINFYSL KQWGNELKNS MSSFRPGRGH 240
SESRRTVFYT NEEWELLDPP PKDLEESLVP EERKKPMPEG SKGVASSGFP FEFGRNPYKG 300
KRPLKDIIGS YKNRHSSSDP LLEGTATSSG SSGGPTKPVP EMQLQIQSQQ EELEQLKKDL 360
SSQKELIRLL QQTVRSSQYD KYFTNPQISQ GVPGDTLELL HQKDEQILGL SGQLERFGLE 420
KESLQQEVRT LKSKVGELNE RLGMLMETIQ AKDEVIIKLS ACEGSVSSPT LGPSSPLAIP 480
ASKDQLELDR LKDSLQGYKS QNKFLNKEIL ELSALRRNAE RRERDLMAKY SSLEAKLCQV 540
ESKYLILLQE MKTPVCSEEQ GPARDVIAQL LEDALQVESQ EQPEQAFVKP HLVSEFDIYG 600
FRTVPDDDEE EKLVAKVRAL DLKTLYLTDN QEVSTGVKWE NYFASTMNRE MACSPELKNL 660
IRAGIPHEHR SKVWKWCVDR HTRKFKDSME PDYFQTLLQK ALEKQNPASK QIELDLLRTL 720
PNNKHYSSPT SEGIQKLRSV LLAFSWRNPD IGYCQGLNRL VAVALLYLDQ EDAFWCLVTI 780
VEVFMPRDYY TKTLLGSQVD QRVFRDLLSE KLPRLHTHFE QYKVDYTLIT FNWFLVVFVD 840
SVVSDILFKI WDSFLYEGPK VIFRFALALF KYKEEEILKL QDSMSIFKYL RYFTRTILDA 900
RKLISISFGD LNPFPLRQIR NRRAYHLEKV RLELTELEAI REDFLRERDT SPDKGELVSD 960
EEEDT 965 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005543; F:phospholipid binding; IEA:InterPro. GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |