CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003715
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 865 
Protein Synonyms/Alias
  
Gene Name
 ZNF865 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
999PACLKAFKDPGYFRKubiquitination[1, 2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
 May be involved in transcriptional regulation (By similarity). 
Sequence Annotation
 ZN_FING 224 246 C2H2-type 1.
 ZN_FING 252 274 C2H2-type 2.
 ZN_FING 350 372 C2H2-type 3.
 ZN_FING 378 400 C2H2-type 4.
 ZN_FING 407 429 C2H2-type 5.
 ZN_FING 441 463 C2H2-type 6.
 ZN_FING 550 572 C2H2-type 7.
 ZN_FING 578 600 C2H2-type 8.
 ZN_FING 606 628 C2H2-type 9.
 ZN_FING 669 691 C2H2-type 10.
 ZN_FING 697 719 C2H2-type 11.
 ZN_FING 792 814 C2H2-type 12.
 ZN_FING 820 842 C2H2-type 13.
 ZN_FING 848 870 C2H2-type 14.
 ZN_FING 876 898 C2H2-type 15.
 ZN_FING 904 926 C2H2-type 16.
 ZN_FING 932 954 C2H2-type 17.
 ZN_FING 960 982 C2H2-type 18.
 ZN_FING 989 1011 C2H2-type 19.
 ZN_FING 1017 1039 C2H2-type 20.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1059 AA 
Protein Sequence
MEANPAGSGA GGGGSSGIGG EDGVHFQSYP FDFLEFLNHQ RFEPMELYGE HAKAVAALPC 60
APGPPPQPPP QPPPPQYDYP PQSTFKPKAE VPSSSSSSSS SSSSSSSSSS SSSSSSSQAK 120
KPDPPLPPAF GAPPPPLFDA AFPTPQWGIV DLSGHQHLFG NLKRGGPASG PGVTPGLGAP 180
AGAPGPLPAP SQTPPGPPAA AACDPTKDDK GYFRRLKYLM ERRFPCGVCQ KSFKQSSHLV 240
QHMLVHSGER PYECGVCGRT YNHVSSLIRH RRCHKDVPPA AGGPPQPGPH LPPLGLPAPA 300
ASAATAAAPS TVSSGPPATP VAPAPSADGS AAPAGVGVPP PATGGGDGPF ACPLCWKVFK 360
KPSHLHQHQI IHTGEKPFSC SVCSKSFNRR ESLKRHVKTH SADLLRLPCG ICGKAFRDAS 420
YLLKHQAAHA GAGAGGPRPV YPCDLCGKSY SAPQSLLRHK AAHAPPAAAA EAPKDGAASA 480
PQPPPTFPPG PYLLPPDPPT TDSEKAAAAA AAVVYGAVPV PLLGAHPLLL GGAGTSGAGG 540
SGASVPGKTF CCGICGRGFG RRETLKRHER IHTGEKPHQC PVCGKRFRES FHLSKHHVVH 600
TRERPYKCEL CGKVFGYPQS LTRHRQVHRL QLPCALAGAA GLPSTQGTPG ACGPGASGTS 660
AGPTDGLSYA CSDCGEHFPD LFHVMSHKEV HMAEKPYGCD ACGKTFGFIE NLMWHKLVHQ 720
AAPERLLPPA PGGLQPPDGS SGTDAASVLD NGLAGEVGAA VAALAGVSGG EDAGGAAVAG 780
AGGGASSGPE RFSCATCGQS FKHFLGLVTH KYVHLVRRTL GCGLCGQSFA GAYDLLLHRR 840
SHRQKRGFRC PVCGKRFWEA ALLMRHQRCH TEQRPYRCGV CGRGFLRSWY LRQHRVVHTG 900
ERAFKCGVCA KRFAQSSSLA EHRRLHAVAR PQRCSACGKT FRYRSNLLEH QRLHLGERAY 960
RCEHCGKGFF YLSSVLRHQR AHEPPRPELR CPACLKAFKD PGYFRKHLAA HQGGRPFRCS 1020
SCGEGFANTY GLKKHRLAHK AENLGGPGAG AGTLAGKDA 1059 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS