CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006833
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein YRO2 
Protein Synonyms/Alias
  
Gene Name
 YRO2 
Gene Synonyms/Alias
 YBR054W; YBR0507 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
94GWIPVRAKYNHVQTSacetylation[1]
104HVQTSTQKEHPGYRQacetylation[1]
286HVGPVAEKKMPSPASubiquitination[2, 3]
295MPSPASFKSSDSDSSubiquitination[4]
304SDSDSSIKEKLKLKKubiquitination[4]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Computational identification of ubiquitylation sites from protein sequences.
 Tung CW, Ho SY.
 BMC Bioinformatics. 2008 Jul 15;9:310. [PMID: 18625080]
 [3] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [4] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
  
Sequence Annotation
 MOD_RES 293 293 Phosphoserine.
 MOD_RES 341 341 Phosphothreonine.
 MOD_RES 343 343 Phosphoserine.
 CROSSLNK 286 286 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Complete proteome; Isopeptide bond; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 344 AA 
Protein Sequence
MSDYVELLKR GGNEAIKINP PTGADFHITS RGSDWLFTVF CVNLLFGVIL VPLMFRKPVK 60
DRFVYYTAIA PNLFMSIAYF TMASNLGWIP VRAKYNHVQT STQKEHPGYR QIFYARYVGW 120
FLAFPWPIIQ MSLLGGTPLW QIAFNVGMTE IFTVCWLIAA CVHSTYKWGY YTIGIGAAIV 180
VCISLMTTTF NLVKARGKDV SNVFITFMSV IMFLWLIAYP TCFGITDGGN VLQPDSATIF 240
YGIIDLLILS ILPVLFMPLA NYLGIERLGL IFDEEPAEHV GPVAEKKMPS PASFKSSDSD 300
SSIKEKLKLK KKHKKDKKKA KKAKKAKKAK KAQEEEEDVA TDSE 344 
Gene Ontology
 GO:0005933; C:cellular bud; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0005216; F:ion channel activity; IEA:InterPro. 
Interpro
 IPR001425; Rhodopsin_arc/bac/fun. 
Pfam
 PF01036; Bac_rhodopsin 
SMART
 SM01021; Bac_rhodopsin 
PROSITE
  
PRINTS