CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024285
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leiomodin-2 
Protein Synonyms/Alias
 Cardiac leiomodin; C-LMOD 
Gene Name
 Lmod2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
79YWEKESQKLLEKERLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 May block the elongation and depolymerization of the actin filaments at the pointed end (By similarity). 
Sequence Annotation
 DOMAIN 523 542 WH2.
 REGION 1 42 Tropomyosin-binding (By similarity).  
Keyword
 Actin-binding; Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 549 AA 
Protein Sequence
MSTFGYRRGL SKYESIDEDE LLASLTAEEL KELERELEDI EPDRNLPVGL RQKSLTEKTP 60
TGNFSREALM AYWEKESQKL LEKERLGECG KLAEEDKEES EEELIFTESN SEVSEEVCTE 120
EEEESTEEEE EEEEEDSEEE EVTTEVTKHI NGTVSHNGVN PDNSKPKTFK SQIENINLTN 180
GNSGGTQRNT ESPAAIHPCG NPTVIEDALE KIKNNDPDTT EVNLNNIENI TTQTLSRFAE 240
ALKENTVVKT FSLANTHADD AAAIAIAEML KVNEHITSVN VESNFITGKG ILAIMRALQH 300
NTVLTELRFH NQRHIMGSQV EMEIVKLLKE NTTLLRLGYH FELPGPRMSM TSILTRNMDK 360
QRQKRMQEQK QQEGHDGGAT LRTKVWQRGT PGSSPYASPR QSPWSSPKVS KKVHTGRSRP 420
PSPVAPPPPP PPPPLPPHML PPPPPPPAPP LPGKKLITRN IAEVIKQQES AQRALQNGQR 480
KKKGKKVKKQ PNNILKEIKN SLRSVQEKKM EESSRPSTPQ RSAHENLMEA IRGSSIRQLR 540
RVEVPEALR 549 
Gene Ontology
 GO:0005856; C:cytoskeleton; IEA:InterPro. 
Interpro
 IPR004934; Tropomodulin. 
Pfam
 PF03250; Tropomodulin 
SMART
  
PROSITE
 PS51082; WH2 
PRINTS