| Tag | Content |
|---|
| CPLM ID | CPLM-007179 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kinetochore-associated protein MTW1 |
Protein Synonyms/Alias | Mis12-like protein |
Gene Name | MTW1 |
Gene Synonyms/Alias | DSN3; NSL2; YAL034W-A; YAL034AW |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 110 | VFRLENQKDLVIVDE | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules. |
Sequence Annotation | |
Keyword | Cell cycle; Cell division; Centromere; Chromosome; Coiled coil; Complete proteome; Kinetochore; Mitosis; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 289 AA |
Protein Sequence | MSAPTMRSTS ILTEHLGYPP ISLVDDIINA VNEIMYKCTA AMEKYLLSKS KIGEEDYGEE 60
IKSGVAKLES LLENSVDKNF DKLELYVLRN VLRIPEEYLD ANVFRLENQK DLVIVDENEL 120
KKSEEKLREK VNDVELAFKK NEMLLKRVTK VKRLLFTIRG FKQKLNELLK CKDDVQLQKI 180
LESLKPIDDT MTLLTDSLRK LYVDSESTSS TEEVEALLQR LKTNGKQNNK DFRTRYIDIR 240
TNNVLRKLGL LGDKEDEKQS AKPDARTQAG DIVSIDIEEP QLDLLDDVL 289 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |