UniProt Accession

 RB11B_MOUSE; P46638 

Genbank Protein ID

 L26528; BC054753; BC085270 

Genbank Nucleotide ID

 AAC42093.1; AAH54753.1; AAH85270.1 

Protein Name

 Ras-related protein Rab-11B 

Protein Synonyms/Alias

  

Gene Name

 Rab11b 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
24	IGDSGVGKSNLLSRF	ubiquitination	[1]
145	EARAFAEKNNLSFIE	ubiquitination	[1]
179	IYRIVSQKQIADRAA	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity). 

Sequence Annotation

 NP_BIND 18 26 GTP (By similarity).
 NP_BIND 66 70 GTP (By similarity).
 NP_BIND 124 127 GTP (By similarity).
 NP_BIND 154 156 GTP (By similarity).
 MOTIF 40 48 Effector region (By similarity).
 MOD_RES 2 2 N-acetylglycine (By similarity).
 MOD_RES 215 215 Cysteine methyl ester (Potential).
 LIPID 214 214 S-geranylgeranyl cysteine (By
 LIPID 215 215 S-geranylgeranyl cysteine (By  

Keyword

 Acetylation; Cell cycle; Cell membrane; Complete proteome; Cytoplasmic vesicle; Direct protein sequencing; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Prenylation; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0045335; C:phagocytic vesicle; ISS:UniProtKB.
 GO:0030670; C:phagocytic vesicle membrane; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0055038; C:recycling endosome membrane; IDA:UniProtKB.
 GO:0019003; F:GDP binding; ISS:UniProtKB.
 GO:0005525; F:GTP binding; IDA:UniProtKB.
 GO:0003924; F:GTPase activity; IMP:UniProtKB.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0032402; P:melanosome transport; IMP:UniProtKB.
 GO:2001135; P:regulation of endocytic recycling; IMP:UniProtKB.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0033572; P:transferrin transport; IMP:UniProtKB. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003579; Small_GTPase_Rab_type. 

Pfam

 PF00071; Ras 

SMART

 SM00175; RAB 

PROSITE

 PS51419; RAB 

PRINTS

 PR00449; RASTRNSFRMNG.