| Tag | Content |
|---|
| CPLM ID | CPLM-012128 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Metaxin-1 |
Protein Synonyms/Alias | Mitochondrial outer membrane import complex protein 1 |
Gene Name | MTX1 |
Gene Synonyms/Alias | MTX; MTXN |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 190 | GAPLKVHKISNPWQS | ubiquitination | [1] | | 286 | EDEEELEKELYREAR | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity). |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Membrane; Mitochondrion; Mitochondrion outer membrane; Polymorphism; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 466 AA |
Protein Sequence | MLLGGPPRSP RSGTSPKGPW SSTGHVQFGK SPQTWPRRTR PRSPEPAAPS GVRGSTWTRR 60
RDTPRRAGPT ALSRYVGHLW MGRRPPSPEA RGPVPRSSAA SRARRSLASP GISPGPLTAT 120
IGGAVAGGGP RQGRAEAHKE VFPGQRVGKM AAPMELFCWS GGWGLPSVDL DSLAVLTYAR 180
FTGAPLKVHK ISNPWQSPSG TLPALRTSHG EVISVPHKII THLRKEVHTF WIDTKNYVEV 240
TRKWYAEAMP FPLNFFLPGR MQRQYMERLQ LLTGEHRPED EEELEKELYR EARECLTLLS 300
QRLGSQKFFF GDAPASLDAF VFSYLALLLQ AKLPSGKLQV HLRGLHNLCA YCTHILSLYF 360
PWDGAEVPPQ RQTPAGPETE EEPYRRRNQI LSVLAGLAAM VGYALLSGIV SIQRATPARA 420
PGTRTLGMAE EDEEE 435 |
Gene Ontology | GO:0016021; C:integral to membrane; TAS:ProtInc. GO:0005743; C:mitochondrial inner membrane; IEA:Compara. GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. GO:0005739; C:mitochondrion; IDA:HPA. GO:0044267; P:cellular protein metabolic process; TAS:Reactome. GO:0006626; P:protein targeting to mitochondrion; TAS:Reactome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |