CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039419
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Pcdh12 
Protein Synonyms/Alias
 Protocadherin 12, isoform CRA_b 
Gene Name
 Pcdh12 
Gene Synonyms/Alias
 rCG_49360 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
461DNAPVFEKSRYEVSTacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Cell adhesion; Cell membrane; Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1179 AA 
Protein Sequence
MLLLPFLLGL LGPGSYLFIS GACQEVATVT VKFQVAEEVP SGTVIGKLSQ EPGVEERRGK 60
AGDAFQILQL PQALPIQMNS EDGLLNTSSR LDREKLCRQQ DPCLVSFDVL ATGASALIHV 120
EIQVLDINDH QPQFPKDEQE LEISESASLH TRIPLDRALD QDTGPNSLYS YSLSPSEHFA 180
LDVIVGPDET KHAELVVVKE LDREVHSYFD LVLTAYDNGN PPKSGTSVVK VNVLDSNDNS 240
PVFAESSLAL EIPEDTAPGT LLINLTATDP DQGPNGEVEF FFGKHVSPEV MNTFGIDAKT 300
GQIVLLQPLD YEKNPAYEVD VQARDLGPNS IPGHCKVLIK VLDVNDNAPS IHITWASQMS 360
LVSEDLPRDS FIALVSANDL DSGNNGLVNC WLNQELGHFR LKRTNGNTYM LLTSAMLDRE 420
QWPTYTLTVF AQDQGPQALS AEKELQIQVS DVNDNAPVFE KSRYEVSTWE NNPPSLHLIT 480
LKAHDADLGS NGKVSYRIKD SPVSHLVIID SETGEVTAQR SLDYEEMAGF EFQVIAEDRG 540
QPQLSSSISV WVSLLDANDN TPEVIQPALS EGKATLSVLV NASTGHLLLP IESPSGMDPA 600
GTGPTPPKAT HSPWSFLLVT IVARDADSGA NGELLYSIQS GNDAHLFVLS PSLGQLFINV 660
TNASSLIGSQ WDLGIVVEDQ GSPSLQTQVS LKVVFVTSMD HLRDSAHEPG ILSTPALAMI 720
CLAVLLAVFG LILALLVSIC RIEKRDNRAY NCREAESMYR HQPKRPQKHI QKADIHLVPM 780
LRAQEDEAEE VRPPHKDTSK ETLMEAGWDS CLQAPFHLTP TLYRTLRNQG NQGALAESQE 840
VLQDTFNFLF NHPRQRNASR ENLNLPESPP TLRQPLLKPL KVPGSPIARV TGDQGSKEAP 900
QSPPASSATL RRQRNLNGKV SPKGESSPHQ ILRSLVRLSV AAFAERNPVE ELAGDSPPVQ 960
QISQLLSLLH QGQFQPKPNH RGNKYSAKPG SSRATIPDTD GLGIRPGGLS EPDLEEGPPS 1020
PEEDLSVKRL LEEELSSLLD PNTGLALDKL SPPDPAWMAR LSLPLTTNYR DNLSSPDAAA 1080
SEEPRTFQTF GKTVGPGPEL SATGTRLAST FVSEMSSLLE MLLEQNTVPV EAASAALRRL 1140
SVCGRTLSLD LATSGASGSE AQLGRKKAAE SSLGCGRNL 1179 
Gene Ontology
 GO:0005911; C:cell-cell junction; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0016339; P:calcium-dependent cell-cell adhesion; IEA:Compara.
 GO:0005977; P:glycogen metabolic process; IEA:Compara.
 GO:0007156; P:homophilic cell adhesion; IEA:Compara.
 GO:0060711; P:labyrinthine layer development; IEA:Compara.
 GO:0007283; P:spermatogenesis; NAS:RGD. 
Interpro
 IPR002126; Cadherin.
 IPR015919; Cadherin-like.
 IPR020894; Cadherin_CS.
 IPR013164; Cadherin_N. 
Pfam
 PF00028; Cadherin
 PF08266; Cadherin_2 
SMART
 SM00112; CA 
PROSITE
 PS00232; CADHERIN_1
 PS50268; CADHERIN_2 
PRINTS
 PR00205; CADHERIN.