CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041814
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cullin 5 
Protein Synonyms/Alias
 Cullin-5 
Gene Name
 Cul5 
Gene Synonyms/Alias
 mCG_5637 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
149EDILEFIKQAQARVLubiquitination[1]
269LCSNPEDKLQIYRDNubiquitination[1]
307NGVQNYMKYADAKLKubiquitination[1]
799EAIIQIMKMRKKISNubiquitination[1]
803QIMKMRKKISNAQLQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 855 AA 
Protein Sequence
MRSLAWAGRG DHVAGKPEEA RLPGTSSALT ARRSGVPRIP RRGLRGPAGN PGLSRRPGPE 60
RRQVSPRLAR VQVENMATSN LLKNKGSLQF EDKWDFMHPI VLKLLRQESV TKQQWFDLFS 120
DVHAVCLWDD KGSSKIHQAL KEDILEFIKQ AQARVLSHQD DTALLKAYIV EWRKFFTQCD 180
ILPKPFCQLE VTLLGKQSSN KKSNMEDSIV RKLMLDTWNE SIFSNIKNRL QDSAMKLVHA 240
ERLGEAFDSQ LVIGVRESYV NLCSNPEDKL QIYRDNFEKA YLDSTERFYR TQAPSYLQQN 300
GVQNYMKYAD AKLKEEEKRA LRYLETRREC NSVEALMECC VNALVTSFKE TILAECQGMI 360
KRNETEKLHL MFSLMDKVPN GIEPMLKDLE EHIISAGLAD MVAAAETITT DSEKYVEQLL 420
TLFNRFSKLV KEAFQDDPRF LTARDKAYKA VVNDATIFKL ELPLKQKGVG LKTQPESKCP 480
ELLANYCDML LRKTPLSKKL TSEEIEAKLK EVLLVLKYVQ NKDVFMRYHK AHLTRRLILD 540
ISADSEIEEN MVEWLREVGM PADYVNKLAR MFQDIKVSED LNQAFKEMHK NNKLALPADS 600
VNIKILNAGA WSRSSEKVFV SLPTELEDLI PEVEEFYKKN HSGRKLHWHH LMSNGIITFK 660
NEVGQYDLEV TTFQLAVLFA WNQRPREKIS FENLKLATEL PDAELRRTLW SLVAFPKLKR 720
QVLLYDPQVN SPKDFTEGTL FSVNQDFSLI KNAKVQKRGK INLIGRLQLT TERMREEENE 780
GIVQLRILRT QEAIIQIMKM RKKISNAQLQ TELVEILKNM FLPQKKMIKE QMEWLIEHRY 840
IRRDEADINT FIYMA 855 
Gene Ontology
 GO:0031466; C:Cul5-RING ubiquitin ligase complex; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0051480; P:cytosolic calcium ion homeostasis; IEA:Compara.
 GO:0006970; P:response to osmotic stress; IEA:Compara.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR016157; Cullin_CS.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR019559; Cullin_neddylation_domain.
 IPR016159; Cullin_repeat-like_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00888; Cullin
 PF10557; Cullin_Nedd8 
SMART
 SM00182; CULLIN
 SM00884; Cullin_Nedd8 
PROSITE
 PS01256; CULLIN_1
 PS50069; CULLIN_2 
PRINTS