CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025738
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dystroglycan 1 
Protein Synonyms/Alias
  
Gene Name
 Dag1 
Gene Synonyms/Alias
 mCG_140684 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
778ICYRKKRKGKLTLEDubiquitination[1]
780YRKKRKGKLTLEDQAubiquitination[1]
791EDQATFIKKGVPIIFubiquitination[1]
792DQATFIKKGVPIIFAubiquitination[1]
806ADELDDSKPPPSSSMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 893 AA 
Protein Sequence
MSVDNWLLHP LWGQTFLLLL SVAVAQAHWP SEPSEAVRDW KNQLEASMHS VLSDFQEAVP 60
TVVGIPDGTA VVGRSFRVSI PTDLIASSGE IIKVSAAGKE ALPSWLHWDP HSHILEGLPL 120
DTDKGVHYIS VSAARLGANG SHVPQTSSVF SIEVYPEDHN EPQSVRAASS DPGEVVPSAC 180
AADEPVTVLT VILDADLTKM TPKQRIDLLN RMQSFSEVEL HNMKLVPVVN NRLFDMSAFM 240
AGPGNAKKVV ENGALLSWKL GCSLNQNSVP DIRGVETPAR EGAMSAQLGY PVVGWHIANK 300
KPTLPKRLRR QIHATPTPVT AIGPPTTAIQ EPPSRIVPTP TSPAIAPPTE TMAPPVRDPV 360
PGKPTVTIRT RGAIIQTPTL GPIQPTRVSE AGTTVPGQIR PTLTIPGYVE PTAVITPPTT 420
TTKKPRVSTP KPATPSTDSS TTTTRRPTKK PRTPRPVPRV TTKAPITRLE TASPPTRIRT 480
TTSGVPRGGE PNQRPELKNH IDRVDAWVGT YFEVKIPSDT FYDNEDTTTD KLKLTLKLRE 540
QQLVGEKSWV QFNSNSQLMY GLPDSSHVGK HEYFMHATDK GGLSAVDAFE IHVHKRPQGD 600
KAPARFKARL AGDPAPVVND IHKKIALVKK LAFAFGDRNC SSITLQNITR GSIVVEWTNN 660
TLPLEPCPKE QIIGLSRRIA DENGKPRPAF SNALEPDFKA LSIAVTGSGS CRHLQFIPVA 720
PPSPGSSAAP ATEVPDRDPE KSSEDDVYLH TVIPAVVVAA ILLIAGIIAM ICYRKKRKGK 780
LTLEDQATFI KKGVPIIFAD ELDDSKPPPS SSMPLILQEE KAPLPPPEYP NQSMPETTPL 840
NQDTVGEYTP LRDEDPNAPP YQPPPPFTAP MEGKGSRPKN MTPYRSPPPY VPP 893 
Gene Ontology
 GO:0005604; C:basement membrane; IDA:MGI.
 GO:0070938; C:contractile ring; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0016011; C:dystroglycan complex; IDA:MGI.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0030175; C:filopodium; IEA:Compara.
 GO:0005925; C:focal adhesion; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0045121; C:membrane raft; IDA:MGI.
 GO:0005654; C:nucleoplasm; IEA:Compara.
 GO:0042383; C:sarcolemma; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008307; F:structural constituent of muscle; IEA:Compara.
 GO:0071711; P:basement membrane organization; IMP:MGI.
 GO:0060445; P:branching involved in salivary gland morphogenesis; IMP:MGI.
 GO:0071679; P:commissural neuron axon guidance; IMP:MGI.
 GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
 GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IMP:MGI.
 GO:0006509; P:membrane protein ectodomain proteolysis; IEA:Compara.
 GO:0034453; P:microtubule anchoring; IEA:Compara.
 GO:0002011; P:morphogenesis of an epithelial sheet; IMP:MGI.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:0043409; P:negative regulation of MAPK cascade; IEA:Compara.
 GO:0051898; P:negative regulation of protein kinase B signaling cascade; IEA:Compara.
 GO:0006607; P:NLS-bearing substrate import into nucleus; IEA:Compara.
 GO:0019048; P:virus-host interaction; IEA:Compara. 
Interpro
 IPR027468; Alpha-dystroglycan_domain_2.
 IPR006644; Cadg.
 IPR015919; Cadherin-like.
 IPR008465; DAG1.
 IPR013783; Ig-like_fold. 
Pfam
 PF05454; DAG1 
SMART
 SM00736; CADG 
PROSITE
  
PRINTS