| Tag | Content |
|---|
| CPLM ID | CPLM-015704 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | D-tagatose-1,6-bisphosphate aldolase subunit GatY |
Protein Synonyms/Alias | TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase |
Gene Name | gatY |
Gene Synonyms/Alias | STM3253 |
Created Date | July 27, 2013 |
Organism | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
NCBI Taxa ID | 99287 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 264 | RHYMQPAKQAMKEVV | acetylation | [1] | | 268 | QPAKQAMKEVVRKVI | acetylation | [1] |
|
Reference | [1] Regulation of cellular metabolism by protein lysine acetylation. Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL. Science. 2010 Feb 19;327(5968):1000-4. [ PMID: 20167786] |
Functional Description | Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol (By similarity). |
Sequence Annotation | REGION 209 211 Dihydroxyacetone phosphate binding (By
REGION 230 233 Dihydroxyacetone phosphate binding (By
ACT_SITE 82 82 Proton donor (By similarity).
METAL 83 83 Zinc; catalytic (By similarity).
METAL 180 180 Zinc; catalytic (By similarity).
METAL 208 208 Zinc; catalytic (By similarity).
BINDING 181 181 Dihydroxyacetone phosphate; via amide |
Keyword | Complete proteome; Galactitol metabolism; Lyase; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 284 AA |
Protein Sequence | MFIISSKNML QKAQHAGYAV PAFNIHNLET LQVVVETAAE MRSPLIVAGT PGTFSYAGMG 60
NIVAIAGDLA REYNLPLAIH LDHHESLADI ESKVMAGIRS VMIDGSHFPF EENVALVKSV 120
VDFCHRYDTS VEAELGRLGG IEDDLVVDSK DALYTNPQQA REFVARTGID SLAVAIGTAH 180
GMYAAEPKLD FERLAEIRAL VDIPLVLHGA SGLPESDIRQ AISLGVCKVN VATELKIAFS 240
DALKEYFLQN PKANDPRHYM QPAKQAMKEV VRKVIHVCGC EGQL 284 |
Gene Ontology | GO:0009025; F:tagatose-bisphosphate aldolase activity; IEA:HAMAP. GO:0008270; F:zinc ion binding; IEA:HAMAP. GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway. GO:0019404; P:galactitol catabolic process; IEA:HAMAP. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |