CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031813
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Calcium-transporting ATPase, putative 
Protein Synonyms/Alias
  
Gene Name
 TGME49_030420, TGVEG_025160 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
483APGSQGMKFTRLGEPacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Hydrolase; Membrane; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1093 AA 
Protein Sequence
MDLSNEKAVG ALSKHRASPN SESGTVSSSP DLLSSLQDVN IHTKAHVLDA EEVVRQLKAD 60
AKRGLSEADA CERLELFGKN ELEQEPGKSL LQLILEQFQD LLVRILLSAA VVSFILALFE 120
GGADEGVTAF IEPLVILIIL ILNAAVGVWQ ESNAEKALEA LKELQPAQGR VLRGGVWRLL 180
PSANLVPGDI IDVRCGDKVP ADCRVLALKS TTLRVEQSQL TGESVTVNKD AEVLAASYED 240
CEVQSKSNLL FSSTTVASGH AVAVVVATGM RTEIGKIQSA VQEAGADDED QTPLQQKLDE 300
FGEILSKVIF VICIVVWVIN IKHFSDPVHG GFLRGCIYYF KIAVALAVAA IPEGLPAVIT 360
TCLALGTRKM AKKNAIVRKL ASVETLGCTT VICSDKTGTL TTNEMTCVRF CVPNMRHGTD 420
EYTCEGSCYS PIGAVNYAGS SHSQRRKFHH IEETDQNLQW LARCATLCNE ARLEIAPGSQ 480
GMKFTRLGEP TEAALLVLVE KLGCTDSTLN ARFLQCEGRK EQAPMPFCDY WASSWNSLAT 540
LEFTRERKSM SVLCRERNSS QNTLFVKGAP ESVLERCTSV LLPNGTVTAL TEGIRKKIQN 600
DVDTMAADAL RTLALAMKRD CGELADYDSA SPSESRHPAR KLLEDAANFA KIESDLIFLG 660
LVGLMDPPRP EVSAAIDACR GAGIKVVMIT GDNKLTAEAV ASMIHIVDDG CVGNCSFTGK 720
EFEGLSLEEK KEVLSQDGVV FSRTEPKHKQ MIIRLLRELG ETTAMTGDGV NDAPALKQAD 780
IGVAMGIAGT EVAKEAADMV LADDNFSTIV AAVEEGRSIY NNMKAFIRYL ISSNIGEVAS 840
IFFTAALGVP EGLSPVQLLW VNLVTDGPPA TALGFNPPDL DVMKREPRHR EDKLISNWIF 900
LRYLLIGIYV GLSTVGIFVS WFVTGLDNGA DPHTLVSLKQ LMHWNECPSW EDFQVAPVYG 960
MKADDPCSFF TVGKVKASSL SLTVLVVIEM FNAFNALSED ASLLQLPPWT NPYLVVATVL 1020
SIAVHCCILY IPFLSRVFGV VPLTAVDWVY VVVWSLPVIF IDEGLKAIGR MKEAARRRQL 1080
SLSRSQSQLR KLQ 1093 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005388; F:calcium-transporting ATPase activity; IEA:EC.
 GO:0046872; F:metal ion binding; IEA:InterPro. 
Interpro
 IPR006068; ATPase_P-typ_cation-transptr_C.
 IPR004014; ATPase_P-typ_cation-transptr_N.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR023298; ATPase_P-typ_TM_dom.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00689; Cation_ATPase_C
 PF00690; Cation_ATPase_N
 PF00122; E1-E2_ATPase
 PF08282; Hydrolase_3 
SMART
 SM00831; Cation_ATPase_N 
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.