CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042683
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Fatty acid desaturase 1 
Protein Synonyms/Alias
  
Gene Name
 FADS1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48RWLVIDRKVYNISEFubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 175 AA 
Protein Sequence
XGVARPAMAP DPVAAETAAQ GPTPRYFTWD EVAQRSGCEE RWLVIDRKVY NISEFTRRHP 60
GGSRVISHYA GQDATKELTD EFRELRATVE RMGLMKANHV FFLLYLLHIL LLDGAAWLTL 120
WVFGTSFLPF LLCAVLLSAV QAQAGWLQHD FGHLSVFSTS KWNHLLHHFV IGHLK 175 
Gene Ontology
 GO:0020037; F:heme binding; IEA:InterPro. 
Interpro
 IPR001199; Cyt_B5-like_heme/steroid-bd. 
Pfam
 PF00173; Cyt-b5 
SMART
  
PROSITE
 PS50255; CYTOCHROME_B5_2 
PRINTS