CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039989
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 84 
Protein Synonyms/Alias
  
Gene Name
 ZNF84 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
274CGKAFSQKSQLTSHQubiquitination[1]
302CGKAFSRKSHLISHWubiquitination[1]
316WRTHTGEKPYGCNECubiquitination[1]
330CGRAFSEKSNLINHQubiquitination[1]
386CRKAFFEKSELIRHQubiquitination[1, 2]
554CGKAFGEKSSLATHQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 737 AA 
Protein Sequence
MTMLQESFSF DDLSVDFTQK EWQLLDPSQK NLYKDVMLEN YSSLVSLGYE VMKPDVIFKL 60
EQGEEPWVGD GEIPSSDSPV WKVDGNMMWH QDNQDKLKII KRGHECDAFG KNFNLNMNFV 120
PLRKSNSEGD LDGLILKHHL DLLIPKGDYG KAESDDFNVF DNFFLHSKPE DTDTWLKYYD 180
CDKYKESYKK SQIIIYHRNR LGEKLYECSE CRKRFSKKPS LIKHQSRHIR DIAFGCGNCG 240
KTFPQKSQFI THHRTHTGEK PYNCSQCGKA FSQKSQLTSH QRTHTGEKPY ECGECGKAFS 300
RKSHLISHWR THTGEKPYGC NECGRAFSEK SNLINHQRIH TGEKPFECRE CGKAFSRKSQ 360
LVTHHRTHTG TKPFGCSDCR KAFFEKSELI RHQTIHTGEK PYECSECRKA FRERSSLINH 420
QRTHTGEKPH GCIQCGKAFS QKSHLISHQM THTGEKPFIC SKCGKAFSRK SQLVRHQRTH 480
TGEKPYECSE CGKAFSEKLS LTNHQRIHTG EKPYVCSECG KAFCQKSHLI SHQRTHTGEK 540
PYECSECGKA FGEKSSLATH QRTHTGEKPY ECRDCEKAFS QKSQLNTHQR IHTGEKPYEC 600
SLCRKAFFEK SELIRHLRTH TGEKPYECNE CRKAFREKSS LINHQRIHTG EKPFECSECG 660
KAFSRKSHLI PHQRTHTGEK PYGCSECRKA FSQKSQLVNH QRIHTGEKPY RCIECGKAFS 720
QKSQLINHQR THTVKKS 737 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS