CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029976
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Voltage-dependent L-type calcium channel subunit alpha-1F 
Protein Synonyms/Alias
  
Gene Name
 Cacna1f 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1158YQNCELDKNQRQCVEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Calcium channel; Calcium transport; Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transport; Voltage-gated channel. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1977 AA 
Protein Sequence
MSESEVGKDT TPEPSPANGT GPGPEWGLCP GPPTVGTDTS GASGLGTPRR RTQHNKHKTV 60
AVASAQRSPR ALFCLTLTNP IRRSCISIVE WKPFDILILL TIFANCVALG VYIPFPEDDS 120
NTANHNLEQV EYVFLVIFTV ETVLKIVAYG LVLHPSAYIR NGWNLLDFII VVVGLFSVLL 180
EQGPGRPGDA PHTGGKPGGF DVKALRAFRV LRPLRLVSGV PSLHIVLNSI MKALVPLLHI 240
ALLVLFVIII YAIIGLELFL GRMHKTCYFL GSDMEAEEDP SPCASSGSGR SCTLNHTECR 300
GRWPGPNGGI TNFDNFFFAM LTVFQCITME GWTDVLYWMQ DAMGYELPWV YFVSLVIFGS 360
FFVLNLVLGV LSGEFSKERE KAKARGDFQK LREKQQMEED LRGYLDWITQ AEELDLHDPS 420
VDGNLASLAE EGRAGHRPQL SELTNRRRGR LRWFSHSTRS THSTSSHASL PASDTGSMTD 480
TPGDEDEEEG TMASCTRCLN KIMKTRICRH FRRANRGLRA RCRRAVKSNA CYWAVLLLVF 540
LNTLTIASEH HGQPLWLTQT QEYANKVLLC LFTVEMLLKL YGLGPSVYVA SFFNRFDCFV 600
VCGGILETTL VEVGAMQPLG ISVLRCVRLL RIFKVTRHWA SLSNLVASLL NSMKSIASLL 660
LLLFLFIIIF SLLGMQLFGG KFNFDQTHTK RSTFDTFPQA LLTVFQILTG EDWNVVMYDG 720
IMAYGGPFFP GMLVCVYFII LFICGNYILL NVFLAIAVDN LASGDAGTAK DKGREKSSEG 780
NPPKENKVLV PGGENEDAKG ARSEGAAPGM EEEEEEEEEE EEEEEEENGA GHVELLQEVV 840
PKEKVVPIPE GSAFFCLSQT NPLRKACHTL IHHHIFTSLI LVFIILSSVS LAAEDPIRAH 900
SFRNHILGYF DYAFTSIFTV EILLKMTVFG AFLHRGSFCR SWFNLLDLLV VSVSLISFGI 960
HSSAISVVKI LRVLRVLRPL RAINRAKGLK HVVQCVFVAI RTIGNIMIVT TLLQFMFACI 1020
GVQLFKGKFY SCTDEAKHTL KECKGSFLIY PDGDVSRPLV RERLWVNSDF NFDNVLSAMM 1080
ALFTVSTFEG WPALLYKAID ANAEDEGPIY NYHVEISVFF IVYIIIIAFF MMNIFVGFVI 1140
ITFRAQGEQE YQNCELDKNQ RQCVEYALKA QPLRRYIPKN PHQYRVWATV NSAAFEYLMF 1200
LLILLNTVAL AMQHYEQTAP FNYAMDILNM VFTGLFTIEM VLKIIAFKPK HYFADAWNTF 1260
DALIVVGSVV DIAVTEVNSS EDSSRISITF FRLFRVMRLV KLLSKGEGIR TLLWTFIKSF 1320
QALPYVALLI AMIFFIYAVI GMQMFGKVAL QDGTQINRNN NFQTFPQAVL LLFRCATGEA 1380
WQEIMLASLP GNRCDPESDF GPGEEFTCGS SFAIVYFISF FMLCAFLIIN LFVAVIMDNF 1440
DYLTRDWSIL GPHHLDEFKR IWSEYDPGAK GRIKHLDVVA LLRRIQPPLG FGKLCPHRVA 1500
CKRLVAMNVP LNSDGTVTFN ATLFALVRTS LKIKTEGNLD QANQELRMVI KKIWKRIKQK 1560
LLDEVIPPPD EEEVTVGKFY ATFLIQDYFR KFRRRKEKGL LGREAPTSTS SALQAGLRSL 1620
QDLGPEIRQA LTYDTEEEEE EEEAVGQEAE EEEAENNPEP YKDSIDSQPQ SRWNSRISVS 1680
LPVKEKLPDS LSTGPSDDDG LAPNSRQPSV IQAGSQPHRR SSGVFMFTIP EEGSIQLKGT 1740
QGQDNQNEEQ EVPDWTPDLD EQAGTPSNPV LLPPHWSQQH VNGHHVPRRR LLPPTPAGRK 1800
PSFTIQCLQR QGSCEDLPIP GTYHRGRTSG PSRAQGSWAA PPQKGRLLYA PLLLVEESTV 1860
GEGYLGKLGG PLRTFTCLQV PGAHPNPSHR KRGSADSLVE AVLISEGLGL FAQDPRFVAL 1920
AKQEIADACH LTLDEMDSAA SDLLAQRTTS LYSDEESILS RFDEEDLGDE MACVHAL 1977 
Gene Ontology
 GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
 GO:0005245; F:voltage-gated calcium channel activity; IMP:MGI.
 GO:0007409; P:axonogenesis; IMP:MGI.
 GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.
 GO:0048813; P:dendrite morphogenesis; IMP:MGI.
 GO:0060041; P:retina development in camera-type eye; IMP:MGI.
 GO:0007601; P:visual perception; IMP:MGI. 
Interpro
 IPR005821; Ion_trans_dom.
 IPR027359; K_channel_four-helix_dom.
 IPR014873; VDCC_a1su_IQ.
 IPR005446; VDCC_L_a1su.
 IPR002077; VDCCAlpha1. 
Pfam
 PF08763; Ca_chan_IQ
 PF00520; Ion_trans 
SMART
 SM01062; Ca_chan_IQ 
PROSITE
  
PRINTS
 PR00167; CACHANNEL.
 PR01630; LVDCCALPHA1.