CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038611
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin-like protein KIF1A 
Protein Synonyms/Alias
  
Gene Name
 Kif1a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
113TMMGKQEKDQQGIIPubiquitination[1]
161VRDLLNPKNKGNLRVubiquitination[1]
201DLMDSGNKARTVAATubiquitination[1]
280KSLTTLGKVISALAEubiquitination[1]
294EMDSGPNKNKKKKKTubiquitination[1]
367INEDPNNKLIRELKDubiquitination[1]
373NKLIRELKDEVTRLRubiquitination[1]
454LNETWEEKLRRTEAIubiquitination[1]
670QRLDYESKLEALQKQubiquitination[1]
676SKLEALQKQMDSRYYubiquitination[1]
910VRQSGTAKISFDDQHubiquitination[1]
920FDDQHFEKFQSESCPubiquitination[1]
1038AFSTEPLKNTGRGPPubiquitination[1]
1398SLLQEVEKTRHYLLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1698 AA 
Protein Sequence
MAGASVKVAV RVRPFNSREM SRDSKCIIQM SGSTTTIVNP KQPKETPKSF SFDYSYWSHT 60
SPEDINYASQ KQVYRDIGEE MLQHAFEGYN VCIFAYGQTG AGKSYTMMGK QEKDQQGIIP 120
QLCEDLFSRI NDTTNDNMSY SVEVSYMEIY CERVRDLLNP KNKGNLRVRE HPLLGPYVED 180
LSKLAVTSYN DIQDLMDSGN KARTVAATNM NETSSRSHAV FNIIFTQKRH DAETNITTEK 240
VSKISLVDLA GSERADSTGA KGTRLKEGAN INKSLTTLGK VISALAEMDS GPNKNKKKKK 300
TDFIPYRDSV LTWLLRENLG GNSRTAMVAA LSPADINYDE TLSTLRYADR AKQIRCNAII 360
NEDPNNKLIR ELKDEVTRLR DLLYAQGLGD ITDMTNALVG MSPSSSLSAL SSRAASVSSL 420
HERILFAPGS EEAIERLKET EKIIAELNET WEEKLRRTEA IRMEREALLA EMGVAMREDG 480
GTLGVFSPKK TPHLVNLNED PLMSECLLYY IKDGVTRVGR EDAERRQDIV LSGHFIKEEH 540
CIFRSDSRGG GEAVVTLEPC EGADTYVNGK KVTEPSILRS GNRIIMGKSH VFRFNHPEQA 600
RQERERTPCA ETPAEPVDWA FAQRELLEKQ GIDMKQEMEQ RLQELEDQYR REREEATYLL 660
EQQRLDYESK LEALQKQMDS RYYPEVNEEE EEPEDEVQWT ERECELALWA FRKWKWYQFT 720
SLRDLLWGNA IFLKEANAIS VELKKKVQFQ FVLLTDTLYS PLPPDLLPPE AAKDRETRPF 780
PRTIVAVEVQ DQKNGATHYW TLEKLRQRLD LMREMYDRAA EVPSSVVEDC DNVVTGGDPF 840
YDRFPWFRLV GRAFVYLSNL LYPVPLVHRV AIVSEKGEVK GFLRVAVQAI SADEEAPDYG 900
SGVRQSGTAK ISFDDQHFEK FQSESCPVVG MSRSGTSQEE LRIVEGQGQG ADAGPSADEV 960
NNNTCSAVPP EGLMDSPEKA ALDGPLDTAL DHLRLGSTFT FRVTVLQASS ISAEYADIFC 1020
QFNFIHRHDE AFSTEPLKNT GRGPPLGFYH VQNIAVEVTK SFIEYIKSQP IVFEVFGHYQ 1080
QHPFPPLCKD VLSPLRPSRR HFPRVMPLSK PVPATKLSTM TRPSPGPCHC KYDLLVYFEI 1140
CELEANGDYI PAVVDHRGGM PCMGTFLLHQ GIQRRITVTL LHETGSHIRW KEVRELVVGR 1200
IRNTPETDEA LIDPNILSLN ILSSGYVHPA QDDRQFLDSD IPRTFYQFEA AWDSSMHNSL 1260
LLNRVTPYRE KIYMTLSAYI EMENCTQPAV ITKDFCMVFY SRDAKLPASR SIRNLFGSGS 1320
LRATEGNRVT GVYELSLCHV ADAGSPGMQR RRRRVLDTSV AYVRGEENLA GWRPRSDSLI 1380
LDHQWELEKL SLLQEVEKTR HYLLLREKLE TTQRPGPEVL SPASSEDSES RSSSGASSPL 1440
SAEGQPSPLE APNERQRELA VKCLRLLMHT FNREYTHSHV CISASESKLS EMSVTLMRDP 1500
SMSPLGAATL TPSSTCPSLI EGRYGATDVR TPQPCSRPAS PEPELLPELD SKKTPSPVRA 1560
TETEKEPQRL LVPDIQEIRV SPIVSKKGYL HFLEPHTAGW AKRFVVVRRP YAYMYNSDKD 1620
TVERFVLNLS TAQVEYSEDQ QAMLKTPNTF AVCTEHRGIL LQANSDKDMH DWLYAFNPLL 1680
AGTIRSKLSR RRSAQMRV 1698 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0043005; C:neuron projection; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008017; F:microtubule binding; IDA:MGI.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR000253; FHA_dom.
 IPR022140; KIF1B.
 IPR022164; Kinesin-like.
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF12473; DUF3694
 PF00498; FHA
 PF12423; KIF1B
 PF00225; Kinesin
 PF00169; PH 
SMART
 SM00240; FHA
 SM00129; KISc
 SM00233; PH 
PROSITE
 PS50006; FHA_DOMAIN
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2
 PS50003; PH_DOMAIN 
PRINTS
 PR00380; KINESINHEAVY.