CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027114
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 HSP90 
Protein Synonyms/Alias
 Heat shock protein 90; Heat shock protein, putative 
Gene Name
 TGGT1_035020, TGME49_088380, TGVEG_082150 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
384RESLQQNKILKVIKKacetylation[1]
559MKEVLHDKVEQVVVSacetylation[1, 2]
Reference
 [1] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842]
 [2] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 708 AA 
Protein Sequence
MADTETFAFN ADIQQLMSLI INTFYSNKEI FLRELISNAS DALDKIRYEA ITDPEKLKGA 60
ERLFIRIVPN KQNNTLTIED DGIGMTKAEL VNNLGTIARS GTKAFMEALQ AGGDISMIGQ 120
FGVGFYSAYL VADKVTVVSR HNDDEMYVWE SSAGGSFTVS KAEGQFENIV RGTRIILHMK 180
EDQTEYLEDR RLKDLVKKHS EFISFPIELA VEKSVDKEIT ESEDEEKPAE DAEEKKEEGE 240
EEKKEEGAEK KKKTKKVKEV VVEYEQLNKQ KPLWMRKPED VTWEEYCAFY KSLTNDWEDP 300
LAVKHFSVEG QLEFKALLFL PKRAPFDLFE TRKKRNNVRL YVRRVFIMDD CEDLIPEWLN 360
FVRGVVDSED LPLNISRESL QQNKILKVIK KNLVKKCLEM FQELEEKKED YTKFYEQFSK 420
NLKLGIHEDT SNRNKIAELL RFHTSKSGDD VVSLKEYVDR MKESQKDIYY ITGESRQSVA 480
SSPFLEALRK KGYEVIYMTD PIDEYAVQQL KEFDGKKLRC CTKKGLELED DEEEKKKFEE 540
LKAEFEPLCK LMKEVLHDKV EQVVVSNRIT DSPCVLVTSE YGWSANMERI MKAQALRDNS 600
MTTYMVSKKT MEINPTNPIM EELKKKSNAD KSDKTVKDLI WLLFDTALLT SGFSLDEPTQ 660
FAARIHRMIK LGLSIDEDDE ELRAEEDLPP LEEVEGAVEE TSKMEEVD 708 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR003594; HATPase_ATP-bd.
 IPR019805; Heat_shock_protein_90_CS.
 IPR001404; Hsp90.
 IPR020575; Hsp90_N.
 IPR020568; Ribosomal_S5_D2-typ_fold. 
Pfam
 PF00183; HSP90 
SMART
 SM00387; HATPase_c 
PROSITE
 PS00298; HSP90 
PRINTS
 PR00775; HEATSHOCK90.