CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025932
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin-like modifier-activating enzyme 1 
Protein Synonyms/Alias
  
Gene Name
 UBA1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
105DEFEGLFKQPAENVNubiquitination[1]
119NQYLTDPKFVERTLRubiquitination[1]
194APFWSGPKRCPHPLTubiquitination[1]
250QVPEFTPKSGVKIHVubiquitination[1]
286ATLPSPDKLPGFKMYubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
MGFHHVGQAG LEPLTSGDPS ALASQSAGIT GVSYCAWPGF SIEVGEWGRL EGFPTSRVAV 60
RLVLALFTDG PSNNACGNPF CQLWPHVICL LCLQWARDEF EGLFKQPAEN VNQYLTDPKF 120
VERTLRLAGT QPLEVLEAVQ RSLVLQRPQT WADCVTWACH HWHTQYSNNI RQLLHNFPPD 180
QLTSSGAPFW SGPKRCPHPL TFDVNNPLHL DYVMAAANLF AQTYGLTGSQ DRAAVATFLQ 240
SVQVPEFTPK SGVKIHVSDQ ELQSANASVD DSRLEELKAT LPSPDKLPGF KMYPIDFEKD 300
DDSNFHMDFI VAASNLRAEN YDIPSADRHK SKLIAGKIIP AIATTTAAVV GLVCLELYKV 360
VQGHRQLDSY KNGFLNLALP FFGFSEPLAA PRHQYYNQEW TLWDRFEVQG LQPNGEEMTL 420
KQFLDYFKTE HKLEITMLSQ GVSMLYSFFM PAAKLKERLD QPMTEIVSRV SKRKLGRHVR 480
ALVLELCCND ESGEDVEVPY VRYTIR 506 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0008641; F:small protein activating enzyme activity; IEA:InterPro.
 GO:0006464; P:cellular protein modification process; IEA:InterPro. 
Interpro
 IPR009036; Molybdenum_cofac_synth_MoeB.
 IPR016040; NAD(P)-bd_dom.
 IPR018965; Ub-activating_enz_e1_C.
 IPR023280; Ub-like_act_enz_cat_cys_dom.
 IPR000127; UBact_repeat. 
Pfam
 PF09358; UBA_e1_C
 PF02134; UBACT 
SMART
 SM00985; UBA_e1_C 
PROSITE
  
PRINTS