CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009361
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Carbonic anhydrase 2 
Protein Synonyms/Alias
 Carbonate dehydratase 2 
Gene Name
 can 
Gene Synonyms/Alias
 cynT2; yadF; b0126; JW0122 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
28EDPGFFEKLAQAQKPacetylation[1]
34EKLAQAQKPRFLWIGacetylation[1]
129HIRDIWFKHSSLLGEacetylation[1]
169TIMQSAWKRGQKVTIacetylation[1]
213RHGISNLKLKHANHKacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 METAL 42 42 Zinc.
 METAL 44 44 Zinc.
 METAL 98 98 Zinc.
 METAL 101 101 Zinc.  
Keyword
 3D-structure; Complete proteome; Lyase; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 220 AA 
Protein Sequence
MKDIDTLISN NALWSKMLVE EDPGFFEKLA QAQKPRFLWI GCSDSRVPAE RLTGLEPGEL 60
FVHRNVANLV IHTDLNCLSV VQYAVDVLEV EHIIICGHYG CGGVQAAVEN PELGLINNWL 120
LHIRDIWFKH SSLLGEMPQE RRLDTLCELN VMEQVYNLGH STIMQSAWKR GQKVTIHGWA 180
YGIHDGLLRD LDVTATNRET LEQRYRHGIS NLKLKHANHK 220 
Gene Ontology
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0004089; F:carbonate dehydratase activity; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IDA:EcoCyc.
 GO:0015976; P:carbon utilization; IEA:InterPro. 
Interpro
 IPR001765; Carbonic_anhydrase.
 IPR015892; Carbonic_anhydrase_CS. 
Pfam
 PF00484; Pro_CA 
SMART
 SM00947; Pro_CA 
PROSITE
 PS00704; PROK_CO2_ANHYDRASE_1
 PS00705; PROK_CO2_ANHYDRASE_2 
PRINTS