CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007616
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoserine phosphatase 
Protein Synonyms/Alias
 PSP; PSPase; O-phosphoserine phosphohydrolase 
Gene Name
 SER2 
Gene Synonyms/Alias
 YGR208W; G7744 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
91DNEYRQAKKLFVFDMubiquitination[1]
92NEYRQAKKLFVFDMDubiquitination[1]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
  
Sequence Annotation
 REGION 186 187 Substrate binding (By similarity).
 ACT_SITE 97 97 Nucleophile (By similarity).
 ACT_SITE 99 99 Proton donor (By similarity).
 METAL 97 97 Magnesium (By similarity).
 METAL 99 99 Magnesium; via carbonyl oxygen (By
 METAL 255 255 Magnesium (By similarity).
 BINDING 106 106 Substrate (By similarity).
 BINDING 142 142 Substrate (By similarity).
 BINDING 232 232 Substrate (By similarity).
 BINDING 258 258 Substrate (By similarity).  
Keyword
 Amino-acid biosynthesis; Complete proteome; Hydrolase; Magnesium; Metal-binding; Reference proteome; Serine biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 309 AA 
Protein Sequence
MSKFVITCIA HGENLPKETI DQIAKEITES SAKDVSINGT KKLSARATDI FIEVAGSIVQ 60
KDLKNKLTNV IDSHNDVDVI VSVDNEYRQA KKLFVFDMDS TLIYQEVIEL IAAYAGVEEQ 120
VHEITERAMN NELDFKESLR ERVKLLQGLQ VDTLYDEIKQ KLEVTKGVPE LCKFLHKKNC 180
KLAVLSGGFI QFAGFIKDQL GLDFCKANLL EVDTDGKLTG KTLGPIVDGQ CKSETLLQLC 240
NDYNVPVEAS CMVGDGGNDL PAMATAGFGI AWNAKPKVQK AAPCKLNTKS MTDILYILGY 300
TDDEIYNRQ 309 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0000287; F:magnesium ion binding; IBA:RefGenome.
 GO:0004647; F:phosphoserine phosphatase activity; IMP:SGD.
 GO:0006564; P:L-serine biosynthetic process; IMP:SGD. 
Interpro
 IPR023214; HAD-like_dom.
 IPR006383; HAD-SF_hydro_IB_PSP-like.
 IPR023190; Pser_Pase_dom_2.
 IPR004469; SerB. 
Pfam
 PF00702; Hydrolase 
SMART
  
PROSITE
  
PRINTS