CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020112
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 670 
Protein Synonyms/Alias
  
Gene Name
 ZNF670 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
204YKCKHCDKAFNYSSYmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 4 90 KRAB.
 ZN_FING 103 125 C2H2-type 1.
 ZN_FING 141 163 C2H2-type 2.
 ZN_FING 197 219 C2H2-type 3.
 ZN_FING 225 247 C2H2-type 4.
 ZN_FING 253 275 C2H2-type 5.
 ZN_FING 281 303 C2H2-type 6.
 ZN_FING 309 331 C2H2-type 7.
 ZN_FING 337 359 C2H2-type 8.
 ZN_FING 365 387 C2H2-type 9; degenerate.
 MOD_RES 281 281 Phosphotyrosine.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 389 AA 
Protein Sequence
MDSVSFEDVA VAFTQEEWAL LDPSQKNLYR DVMQEIFRNL ASVGNKSEDQ NIQDDFKNPG 60
RNLSSHVVER LFEIKEGSQY GETFSQDSNL NLNKKVSTGV KPCECSVCGK VFICHSALHR 120
HILSHIGNKL FECEECPEKL YHCKQCGKAF ISLTSVDRHM VTHTSNGPYK GPVYEKPFDF 180
PSVFQMPQST YTGEKTYKCK HCDKAFNYSS YLREHERTHT GEKPYACKKC GKSFTFSSSL 240
RQHERSHTGE KPYECKECGK AFSRSTYLGI HERTHTGEKP YECIKCGKAF RCSRVLRVHE 300
RTHSGEKPYE CKQCGKAFKY SSNLCEHERT HTGVKPYGCK ECGKSFTSSS ALRSHERTHT 360
GEKPYECKKC GKAFSCSSSL RKHERAYMW 389 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS