UniProt Accession

 F6QHF1_MOUSE; F6QHF1 

Genbank Protein ID

 CR974422 

Genbank Nucleotide ID

  

Protein Name

 Antigen peptide transporter 1 

Protein Synonyms/Alias

  

Gene Name

 Tap1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
45	NEEGEAQKFRQKLEE	ubiquitination	[1]
123	KAVGSSEKIFEYLDR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 196 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005886; C:plasma membrane; IBA:RefGenome.
 GO:0042825; C:TAP complex; IBA:RefGenome.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.
 GO:0042605; F:peptide antigen binding; IBA:RefGenome.
 GO:0046978; F:TAP1 binding; IBA:RefGenome.
 GO:0046979; F:TAP2 binding; IBA:RefGenome.
 GO:0046980; F:tapasin binding; IBA:RefGenome.
 GO:0006952; P:defense response; IMP:MGI.
 GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome. 

Interpro

 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00664; ABC_membrane 

SMART

  

PROSITE

 PS50929; ABC_TM1F 

PRINTS