CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028282
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 26S proteasome regulatory complex subunit p37A 
Protein Synonyms/Alias
 AT10619p; LD24440p; Ubiquitin C-terminal hydrolase, isoform A; Ubiquitin C-terminal hydrolase, isoform B 
Gene Name
 Uch-L5 
Gene Synonyms/Alias
 Uch-L3; CG31639; CG3431; Dmel_CG3431 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
156LDTKNQKKDDDVYHFacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 324 AA 
Protein Sequence
MGDGAGNWCL IESDPGVFTE LIREFGCDGA QVEEIWSLDS ESFKNLEPIH GLIFLFKWVQ 60
EDEPAGKVVL DRENIFFAKQ VINNACATQA ILSLLMNLDH EDIKLGETLT NFKEFCQCFD 120
PYNKGLTLSN ASQIRTVHNS FARPTLFELD TKNQKKDDDV YHFVGYMPIG GRLYELDGLR 180
EGPIDLGEIK SEQNWIDVVR PIIEKRMQRY SDGEIHFNLM ALISDRQRIY EQQIEKLLNP 240
APNAMDTEED RQAEISSLRT YIEYEIQKKK RYKVENVRRK HNYLPFIVEL LKILGENGQL 300
MPIYEKAKQR ALEREQAQRK KDTD 324 
Gene Ontology
 GO:0005838; C:proteasome regulatory particle; IDA:FlyBase.
 GO:0008242; F:omega peptidase activity; IEA:InterPro.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:EC.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:FlyBase.
 GO:0016579; P:protein deubiquitination; IDA:FlyBase. 
Interpro
 IPR001578; Peptidase_C12.
 IPR017390; Ubiquitinyl_hydrolase_UCH37. 
Pfam
 PF01088; Peptidase_C12 
SMART
  
PROSITE
  
PRINTS
 PR00707; UBCTHYDRLASE.