Tag | Content |
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CPLM ID | CPLM-014466 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription initiation factor TFIID subunit 9B |
Protein Synonyms/Alias | Neuronal cell death-related gene in neuron 7; DN-7; Transcription initiation factor TFIID subunit 9-like; Transcription-associated factor TAFII31L |
Gene Name | Taf9b |
Gene Synonyms/Alias | Dn7; Taf9l |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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108 | QTPLPLIKPYAGPRL | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Essential for cell viability. TAF9 and TAF9L are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity). |
Sequence Annotation | MOD_RES 156 156 Phosphothreonine (By similarity). MOD_RES 159 159 Phosphothreonine (By similarity). MOD_RES 174 174 Phosphothreonine (By similarity). MOD_RES 177 177 Phosphoserine (By similarity). |
Keyword | Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 258 AA |
Protein Sequence | MEPSKMAPLK NAPRDALVMA QILKDMGITD YEPRVINQML EFAFRYVTTI LDDAKIYSSH 60 AKKPTVDADD VRLAIQCRAD QSFTSPPPRD FLLDIARQKN QTPLPLIKPY AGPRLPPDRY 120 CLTAPNYRLK SLVKKGPNQG RLVPRLSVGA VSSRPTTPTV APPQAVSVPN KVATPVSVTS 180 QRFAVQIPTS QSTPAKPAPA ATSVQNVLIN PSMIGSKNIL ITTNMVSSQS TATDSNPLKR 240 KHDDDDDDDD DDDDNDTM 258 |
Gene Ontology | GO:0005669; C:transcription factor TFIID complex; IEA:Compara. GO:0033276; C:transcription factor TFTC complex; IEA:Compara. GO:0006352; P:DNA-dependent transcription, initiation; IEA:InterPro. GO:0043066; P:negative regulation of apoptotic process; IEA:Compara. GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara. GO:0030307; P:positive regulation of cell growth; IEA:Compara. GO:0012501; P:programmed cell death; IEP:RGD. GO:0014070; P:response to organic cyclic compound; IEP:RGD. |
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