CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014466
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription initiation factor TFIID subunit 9B 
Protein Synonyms/Alias
 Neuronal cell death-related gene in neuron 7; DN-7; Transcription initiation factor TFIID subunit 9-like; Transcription-associated factor TAFII31L 
Gene Name
 Taf9b 
Gene Synonyms/Alias
 Dn7; Taf9l 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
108QTPLPLIKPYAGPRLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Essential for cell viability. TAF9 and TAF9L are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription (By similarity). 
Sequence Annotation
 MOD_RES 156 156 Phosphothreonine (By similarity).
 MOD_RES 159 159 Phosphothreonine (By similarity).
 MOD_RES 174 174 Phosphothreonine (By similarity).
 MOD_RES 177 177 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 258 AA 
Protein Sequence
MEPSKMAPLK NAPRDALVMA QILKDMGITD YEPRVINQML EFAFRYVTTI LDDAKIYSSH 60
AKKPTVDADD VRLAIQCRAD QSFTSPPPRD FLLDIARQKN QTPLPLIKPY AGPRLPPDRY 120
CLTAPNYRLK SLVKKGPNQG RLVPRLSVGA VSSRPTTPTV APPQAVSVPN KVATPVSVTS 180
QRFAVQIPTS QSTPAKPAPA ATSVQNVLIN PSMIGSKNIL ITTNMVSSQS TATDSNPLKR 240
KHDDDDDDDD DDDDNDTM 258 
Gene Ontology
 GO:0005669; C:transcription factor TFIID complex; IEA:Compara.
 GO:0033276; C:transcription factor TFTC complex; IEA:Compara.
 GO:0006352; P:DNA-dependent transcription, initiation; IEA:InterPro.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0030307; P:positive regulation of cell growth; IEA:Compara.
 GO:0012501; P:programmed cell death; IEP:RGD.
 GO:0014070; P:response to organic cyclic compound; IEP:RGD. 
Interpro
 IPR009072; Histone-fold.
 IPR003162; TFIID-31. 
Pfam
 PF02291; TFIID-31kDa 
SMART
  
PROSITE
  
PRINTS