CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044672
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphatidylinositol transfer protein alpha isoform 
Protein Synonyms/Alias
  
Gene Name
 Pitpna 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
112MKEDFLIKIETWHKPubiquitination[1]
136KLEPEAWKHVEAIYIacetylation[2]
154DRSQVLSKDYKAEEDubiquitination[1]
164KAEEDPAKFKSVKTGubiquitination[1]
180GPLGPNWKQELVNQKacetylation[2]
180GPLGPNWKQELVNQKubiquitination[1]
196CPYMCAYKLVTVKFKacetylation[2]
201AYKLVTVKFKWWGLQacetylation[2]
203KLVTVKFKWWGLQNKacetylation[2, 3]
203KLVTVKFKWWGLQNKsuccinylation[3]
203KLVTVKFKWWGLQNKubiquitination[1]
210KWWGLQNKVENFIHKacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 272 AA 
Protein Sequence
MVLLKEYRVI LPVSVDEYQV GQLYSVAEAS KNETGGGEGV EVLVNEPYEK DDGEKGQYTH 60
KIYHLQSKVP TFVRMLAPEG ALNIHEKAWN AYPYCRTVIT KNEYMKEDFL IKIETWHKPD 120
LGTQENVHKL EPEAWKHVEA IYIDIADRSQ VLSKDYKAEE DPAKFKSVKT GRGPLGPNWK 180
QELVNQKDCP YMCAYKLVTV KFKWWGLQNK VENFIHKQEK RLFTNFHRQL FCWLDKWVDL 240
TMDDIRRMEE ETKRQLDEMR QKDPVKGMTA DD 272 
Gene Ontology
 GO:0016021; C:integral to membrane; ISS:MGI.
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005543; F:phospholipid binding; ISO:MGI.
 GO:0006810; P:transport; IEA:InterPro. 
Interpro
 IPR001666; PI_transfer.
 IPR023393; START-like_dom. 
Pfam
 PF02121; IP_trans 
SMART
  
PROSITE
  
PRINTS
 PR00391; PITRANSFER.