CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026466
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glutaminyl-tRNA synthetase 
Protein Synonyms/Alias
 Protein Qars; RCG25149, isoform CRA_a 
Gene Name
 RGD1562301 
Gene Synonyms/Alias
 Qars; rCG_25149 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
628EESEPGYKRLAWGQPacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; Nucleotide-binding; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 775 AA 
Protein Sequence
MATPDSLALF TGLGLSENKA RETLKNAALS TQLREAATQA QQTLGSTIDK ATGTLLYGLA 60
SRLRDTRRLS FLVGYIANKK IHTELQLSAA LEYVRSHPLD PIDTKDFEQE CGVGVVVTPE 120
QIEEAVEATI NRHRPQLLVE RYRFSMGLLM GEARAALRWA DGKMIKNEVD MQVLHLLGPK 180
MEADLEKKPK VAKARLEETD RKTAKDVVEN GEVAGQTLSL MEQLRGEALK FHKPGENYKT 240
PGYVTTPHTM DLLKQHLEIT GGQVRTRFPP EPNGILHIGH AKAINFNFGY AKANNGICFL 300
RFDDTNPEKE EAKFFTAIYD MVTWLGYTPY KVTYASDYFD QLYAWAVELI RRGQAYVCHQ 360
RGEELKGHNP LPSPWRDRPI EESLLLFEAM RKGKFAEGEA TLRMKLVMED GKMDPVAYRV 420
KYTPHHRTGD KWCIYPTYDY THCLCDSIEH ITHSLCTKEF QARRSSYFWL CNALDVYCPV 480
QWEYGRLNLH YAVVSKRKIL QLVAAGAVRD WDDPRLFTLT ALRRRGFPPE AINNFCARVG 540
VTVAQTTMEP HLLEACVRDV LNDTAPRAMA VLEPLQVVIT NFPAPKPLDI RVPNFPADET 600
KGFHQVPFAS TVFIERTDFK EESEPGYKRL AWGQPVGLRH TGYVIELQHV VRGSSGCVEC 660
LEVTCRRADA GEKPKAFIHW VSQPLVCEIR LYERLFQHKN PEDPVEVPGG FLSDLNPASL 720
QVIKGALVDC SVALAKPFDK FQFERLGYFS VDPDSHQGQV VFNRTVTLKE DPGKV 775 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004819; F:glutamine-tRNA ligase activity; IEA:InterPro.
 GO:0006425; P:glutaminyl-tRNA aminoacylation; IEA:InterPro. 
Interpro
 IPR001412; aa-tRNA-synth_I_CS.
 IPR004514; Gln-tRNA-synth_Ib.
 IPR007638; Gln-tRNA-synth_Ib_RNA-bd_2.
 IPR007639; Gln-tRNA-synth_Ib_RNA-bd_N.
 IPR000924; Glu/Gln-tRNA-synth_Ib.
 IPR020061; Glu/Gln-tRNA-synth_Ib_a-bdl.
 IPR020058; Glu/Gln-tRNA-synth_Ib_cat-dom.
 IPR020059; Glu/Gln-tRNA-synth_Ib_codon-bd.
 IPR020056; Rbsml_L25/Gln-tRNA_synth_b-brl.
 IPR011035; Ribosomal_L25/Gln-tRNA_synth.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF00749; tRNA-synt_1c
 PF03950; tRNA-synt_1c_C
 PF04558; tRNA_synt_1c_R1
 PF04557; tRNA_synt_1c_R2 
SMART
  
PROSITE
 PS00178; AA_TRNA_LIGASE_I 
PRINTS
 PR00987; TRNASYNTHGLU.