CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024162
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vesicle-associated membrane protein 5 
Protein Synonyms/Alias
 VAMP-5; Myobrevin 
Gene Name
 Vamp5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
33KVLERHGKLAELEQRubiquitination[1]
53DMSSAFSKTTKTLAQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking. 
Sequence Annotation
 DOMAIN 5 65 v-SNARE coiled-coil homology.
 MOD_RES 48 48 Phosphoserine (By similarity).
 MOD_RES 49 49 Phosphoserine (By similarity).  
Keyword
 Cell membrane; Coiled coil; Complete proteome; Developmental protein; Differentiation; Golgi apparatus; Membrane; Myogenesis; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 102 AA 
Protein Sequence
MAGKELKQCQ QQADEVTEIM LNNFDKVLER HGKLAELEQR SDQLLDMSSA FSKTTKTLAQ 60
QKRWENIRCR VYLGLAVAVG LLIILIVLLV VFLPSGGDSS KP 102 
Gene Ontology
 GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005887; C:integral to plasma membrane; IDA:MGI.
 GO:0005802; C:trans-Golgi network; IEA:Compara.
 GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
 GO:0043001; P:Golgi to plasma membrane protein transport; IMP:MGI.
 GO:0007519; P:skeletal muscle tissue development; IDA:MGI. 
Interpro
 IPR001388; Synaptobrevin.
 IPR016444; Synaptobrevin_met/fun. 
Pfam
 PF00957; Synaptobrevin 
SMART
  
PROSITE
 PS00417; SYNAPTOBREVIN
 PS50892; V_SNARE 
PRINTS
 PR00219; SYNAPTOBREVN.