CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017343
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SIX6OS1 
Protein Synonyms/Alias
 Six6 opposite strand transcript 1 
Gene Name
 SIX6OS1 
Gene Synonyms/Alias
 C14orf39 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
36EMIQRINKCCEDIKEubiquitination[1]
80KDNCRNWKPTCDVFRubiquitination[1]
160LACTEQLKMNETIFMacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Monoclonal antibody cocktail as an enrichment tool for acetylome analysis.
 Shaw PG, Chaerkady R, Zhang Z, Davidson NE, Pandey A.
 Anal Chem. 2011 May 15;83(10):3623-6. [PMID: 21466224
Functional Description
 May be involved in eye development through regulation of the SIX6 transcription factor. 
Sequence Annotation
  
Keyword
 Complete proteome; Developmental protein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 587 AA 
Protein Sequence
MNDSLFVSLD RLLLEFVFQY EQDISTKEEM IQRINKCCED IKENKVTICR IHETINATDE 60
EIDHYCKHSE EIKDNCRNWK PTCDVFRKHE DYMQDQFTVY QGTVEKDKEM YHDYICQYKE 120
VLKQYQLKYS ETPFSREYYE KKREHEEIQS RVLACTEQLK MNETIFMKFR VPAPFPSLTK 180
WTLNIVNLRC ETQDILKHAS NLTKSSSELK KEVDEMEIEI NYLNQQISRH NETKALSETL 240
EEKNKNTENR KELKERIFGK DEHVLTLNKT QSSQLFLPYE SQKLVRPIKM HSSEPRVADI 300
KEESSAKQSK LANIDFRQKE NDTQIFNDSA VDNHSKCSHI TTITSSQKFM QVRLLTPQKQ 360
SNSNQWSEKG DKDAEYGDKG TVRQVRESKC TSQAIYTEHF GKSVENDSDE VEERAENFPR 420
TSEIPIFLGT PKAVKAPESL EKIKFPKTPP FEINRNRNAV PEVQTEKESP GLSFLMSYTS 480
RSPGLNLFDS SVFDTEISSD QFNEHYSARN LNPLSSEQEI GNLLEKPEGE DGFTFSFPSD 540
TSTHTFGAGK DDFSFPFSFG QGQNSIPSSS LKGFSSSSQN TTQFTFF 587 
Gene Ontology
 GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
 GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; NAS:UniProtKB. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS