UniProt Accession

 CXCL9_HUMAN; Q07325; Q503B4 

Genbank Protein ID

 X72755; BC063122; BC095396 

Genbank Nucleotide ID

 CAA51284.1; AAH63122.1; AAH95396.1 

Protein Name

 C-X-C motif chemokine 9 

Protein Synonyms/Alias

 Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9 

Gene Name

 CXCL9 

Gene Synonyms/Alias

 CMK; MIG; SCYB9 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
2	******MKKSGVLFL	acetylation	[1]
3	*****MKKSGVLFLL	acetylation	[1]
28	QGTPVVRKGRCSCIS	acetylation	[1]

Reference

 [1] Identification of lysine acetyltransferase p300 substrates using 4-pentynoyl-coenzyme A and bioorthogonal proteomics.
 Yang YY, Grammel M, Hang HC.
 Bioorg Med Chem Lett. 2011 Sep 1;21(17):4976-9. [PMID: 21669532] 

Functional Description

 Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. 

Sequence Annotation

 DISULFID 31 58 By similarity.
 DISULFID 33 74 By similarity.  

Keyword

 Complete proteome; Cytokine; Direct protein sequencing; Disulfide bond; Inflammatory response; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 125 AA 

Protein Sequence

Gene Ontology

 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0005615; C:extracellular space; TAS:ProtInc.
 GO:0008009; F:chemokine activity; TAS:ProtInc.
 GO:0007267; P:cell-cell signaling; TAS:ProtInc.
 GO:0006968; P:cellular defense response; TAS:ProtInc.
 GO:0006935; P:chemotaxis; TAS:ProtInc.
 GO:0051607; P:defense response to virus; IEA:Compara.
 GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0006954; P:inflammatory response; TAS:ProtInc. 

Interpro

 IPR001089; Chemokine_CXC.
 IPR018048; Chemokine_CXC_CS.
 IPR001811; Chemokine_IL8-like_dom.
 IPR027225; CXCL9. 

Pfam

 PF00048; IL8 

SMART

 SM00199; SCY 

PROSITE

 PS00471; SMALL_CYTOKINES_CXC 

PRINTS

 PR00437; SMALLCYTKCXC.