CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011382
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein TOS4 
Protein Synonyms/Alias
 Target of SBF protein 4 
Gene Name
 TOS4 
Gene Synonyms/Alias
 YLR183C; L94705.22 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
22PYSPPNYKQQPNCPSubiquitination[1]
34CPSSNYEKAGKTASEubiquitination[1]
37SNYEKAGKTASESIGubiquitination[1]
197VPRFSNEKCVKEIQDubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Binds to the promoters of genes with functions important for the G1/S (start) transition; primarily genes involved in pheromone response, polarized growth and transcription. 
Sequence Annotation
 DOMAIN 118 170 FHA.
 MOD_RES 40 40 Phosphoserine.  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 489 AA 
Protein Sequence
MSSQFPSSPY RTVDPYSPPN YKQQPNCPSS NYEKAGKTAS ESIGNFGKGD YPTPFPSSSI 60
GRVSSPVRSN KVDAIPSSPA FPGQLAETSP KFSSKLSSPS RHTRVINAEL DPSKISTITV 120
GRNSSQCDVA LCKNKFISRV HASITYLPQT NEVKIHCFSM NGLIVTYRKQ FDCYQLKDTM 180
NNNNRAYRLV PRFSNEKCVK EIQDEGGFIN FTLEEGDTVY MTYYKGIMLD FRQVLLRISL 240
KEKNSSSEPL RFEKKAEFES ESETKHMGSI RKHPLIFTDT SMDRPKKILK DSNKISIGSD 300
SGVAERMLNH FLNSKSSPLS SVSSVDHEEQ TLRQDSLSSD KNPMTMKKPK LNKRVLPSKP 360
KKSVKENLDE LSRRNIDVMH LQHILTNHLA FANVQQTPLF QLQQVNSQIS ELSRDELRSI 420
LSDAKCVGVI YRHGKDAAGK PLDEEYFYDL ENDDDYERRN LVSSLKGGRT GLRSCRRTHK 480
QYFWKKPAK 489 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0070210; C:Rpd3L-Expanded complex; IDA:SGD.
 GO:0003682; F:chromatin binding; IDA:SGD.
 GO:0006974; P:response to DNA damage stimulus; IGI:SGD. 
Interpro
 IPR000253; FHA_dom.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF00498; FHA 
SMART
 SM00240; FHA 
PROSITE
 PS50006; FHA_DOMAIN 
PRINTS