| Tag | Content |
|---|
| CPLM ID | CPLM-007346 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ubiquitin carboxyl-terminal hydrolase 7 |
Protein Synonyms/Alias | Deubiquitinating enzyme 7; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7 |
Gene Name | UBP7 |
Gene Synonyms/Alias | YIL156W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 549 | QVSSISRKPPIPAKQ | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the sorting of ubiquitinated cargo proteins at the multivesicular body (MVB). |
Sequence Annotation | ACT_SITE 618 618 Nucleophile (By similarity).
ACT_SITE 1014 1014 Proton acceptor (By similarity). |
Keyword | Complete proteome; Cytoplasm; Hydrolase; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1071 AA |
Protein Sequence | MLDDDKGTAM HPHITPFTPE YSNELLRRVQ DLYHEDIKHY YPQLKLEKLL DLLEHTEYLF 60
ELYLDSIHHD RPNDALTAFI IGCYYVFLII PQSLQFQTRN KSYSIYTDLK KMYENEMNMT 120
NVVLMVKKEI GVVLDESVKH GAGIEHRITK KRAFSVPADD LSGQVASLSL DTAAPQDHGL 180
KGTFTEDDAE QSSPVWTAPN LEPNDQLKLA LLPEVIPTPA FREPERKTSV PVRPSVLLED 240
VPSIYHEDDT SFASLNPPFR EITADRSVTH RKDSYHSVYM VDSGNLKEDN DDLFNVENDG 300
FIQSLDILQK QSIITAPELF SILSNRVERE KVLLIDLRIP QRSAINHIVA PNLVNVDPNL 360
LWDKQTNTPI YKDDILEHLL KENENFINRN KFDYIVYYTD VKTFMTINFD YAFIFFYLML 420
TSQKTPLTTV PTTLLGGYEK WKKTLHSYAQ EYHISIEDYL YRPYSQKARL QQEQQQQQQQ 480
PDSQDSFSAK ESSTKVPEPP SWKPPDLPIR LRKRPPPPPP VSMPTTPEIP PPLPPKIMVH 540
SQVSSISRKP PIPAKQHVKK EQLNSNEIIQ RKRQHQHQHY DQQILQPQRA YNIPTIERSP 600
NVYVSLSITG LRNLGNTCYI NSMIQCLFAA KTFRTLFISS KYKSYLQPIR SNGSHYSPKL 660
SNSLSMLFNK MYLNGGCSVV PTGFLKVINQ LRPDLKIPDD QQDTQEFLMI LLDRLHDELS 720
DQQHVANDYP NLLLYNADAL KVSNNEYKHW FDKNVIGNGI SPIDDIFQGQ MENSLQCKRC 780
GYTTFNYSTF YVLSLAIPRR SMKLSKLGRS TEKRVKLEDC INMFTSDEVL SGENAWDCPR 840
CGPTASVSTS VSALENEPSI VKSKKKKSRF FTLHTGTKRR HLDFFGDGIT EGHNSNNNNT 900
TIFERERSRS PFRMLGGSGK RSSSSTPFST GGNDSNNSSD YKNKKLTTVK TINFVTLPKI 960
LVIHLSRFYY DLTKKNNTVV TYPLILNIIL KNNDTMKYKL FGVVNHTGTL ISGHYTSLVN 1020
KDLEHNVNIG RSKWYYFDDE VVKADRKHGS DKNLKISSSD VYVLFYERVY D 1071 |
Gene Ontology | GO:0005737; C:cytoplasm; IC:SGD. GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro. GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD. GO:0016579; P:protein deubiquitination; TAS:SGD. GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |